一名66岁未经化疗的女性同时患有急性单核细胞白血病和多发性骨髓瘤。
Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman.
作者信息
Murukutla Srujitha, Arora Swaty, Bhatt Vijaya Raj, Kedia Shiksha, Popalzai Muhammad, Dhar Meekoo
机构信息
Department of Medicine, Staten Island University Hospital, 475 Seaview Avenue, Staten Island, New York 10305, USA.
Sanford R Nalitt Institute for Cancer and Blood Related Diseases, Department of Medicine, Division of Hematology and Oncology, Staten Island University Hospital, 256 Mason Avenue, Staten Island, New York 10305, USA.
出版信息
World J Oncol. 2014 Apr;5(2):68-71. doi: 10.14740/wjon722w. Epub 2014 May 6.
Abstract
Concurrent acute myeloid leukemia (AML) and multiple myeloma (MM) is rare, more so in chemotherapy-naive patients. Concurrent occurrence of these two malignancies portends poor prognosis. Although anthracycline-based AML regimen, allogeneic hematopoietic stem cell transplantation, tipifarnib and bortezomib have shown promising results in small number of patients, there is a lack of established therapy. We describe a case of concurrent AML and MM in a 66-year-old woman and review previously published literature.
摘要
同时发生急性髓系白血病（AML）和多发性骨髓瘤（MM）的情况较为罕见，在未经化疗的患者中更是如此。这两种恶性肿瘤同时出现预示着预后不良。尽管基于蒽环类药物的AML治疗方案、异基因造血干细胞移植、替匹法尼和硼替佐米在少数患者中已显示出有前景的结果，但仍缺乏既定的治疗方法。我们描述了一名66岁女性同时患有AML和MM的病例，并回顾了先前发表的文献。
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本文引用的文献
1
Simultaneous occurrence of multiple myeloma and acute myeloid leukemia.多发性骨髓瘤与急性髓系白血病同时发生。
Turk J Haematol. 2006 Dec 5;23(4):209-11.
2
Simultaneous acute myeloid leukemia and multiple myeloma successfully treated with allogeneic stem cell transplantation.异基因干细胞移植成功治疗同时性急性髓系白血病和多发性骨髓瘤。
South Med J. 2010 Dec;103(12):1246-9. doi: 10.1097/SMJ.0b013e3181fa5eeb.
3
Simultaneous appearance of dual malignancies of hematopoietic system-multiple myeloma and acute myeloid leukemia.造血系统双恶性肿瘤——多发性骨髓瘤和急性髓系白血病同时出现。
Indian J Pathol Microbiol. 2008 Jan-Mar;51(1):118-20. doi: 10.4103/0377-4929.40422.
4
Tipifarnib and bortezomib are synergistic and overcome cell adhesion-mediated drug resistance in multiple myeloma and acute myeloid leukemia.替匹法尼和硼替佐米具有协同作用，可克服多发性骨髓瘤和急性髓性白血病中细胞黏附介导的耐药性。
Clin Cancer Res. 2006 Jan 15;12(2):591-9. doi: 10.1158/1078-0432.CCR-05-1792.
5
Simultaneous presentation of multiple myeloma and acute monocytic leukemia.多发性骨髓瘤与急性单核细胞白血病同时出现。
Arch Pathol Lab Med. 2003 Nov;127(11):1506-8. doi: 10.5858/2003-127-1506-SPOMMA.
6
Reactive plasmacytosis and lymphocytosis in acute myeloid leukemia.急性髓系白血病中的反应性浆细胞增多症和淋巴细胞增多症。
Hematol Pathol. 1994;8(1-2):43-51.
7
[Myeloma together with acute myeloblastic leukaemia in an untreated patient (author's transl)].一名未经治疗患者的骨髓瘤合并急性髓细胞白血病（作者译）
Nouv Presse Med. 1980 Sep 27;9(35):2559-60.
8
Simultaneous presentation of plasma cell and monocytic leukemia with a subacute clinical course.同时出现浆细胞和单核细胞白血病，临床病程呈亚急性。
Acta Haematol. 1982;68(3):249-55. doi: 10.1159/000206988.
9
Simultaneous presentation of acute myelomonocytic leukaemia and multiple myeloma.急性粒单核细胞白血病与多发性骨髓瘤同时出现。
Acta Haematol. 1982;68(2):153-6. doi: 10.1159/000206968.
10
Multiple myeloma and acute myelomonocytic leukemia: simultaneous occurrence without previous chemotherapy.多发性骨髓瘤与急性粒单核细胞白血病：未经前期化疗而同时发生。
Acta Haematol. 1980;64(4):195-200. doi: 10.1159/000207250.
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