基于明胶和氧化葡聚糖相分离的用于3D打印的生理pH依赖性凝胶化
Physiological pH-dependent gelation for 3D printing based on the phase separation of gelatin and oxidized dextran.
作者信息
Du Zengmin, Li Ningfeng, Hua Yujie, Shi Yong, Bao Chunyan, Zhang Hongbo, Yang Yi, Lin Qiuning, Zhu Linyong
机构信息
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130# Meilong Road, Shanghai, 200237, China.
出版信息
Chem Commun (Camb). 2017 Dec 5;53(97):13023-13026. doi: 10.1039/c7cc08225h.
An extrudable hydrogel with a tunable gelation time under physiological pH ranges based on the phase separation of gelatin and oxidized dextran was demonstrated. We envision that the easy handing properties of this hydrogel combined with thermosensitive physical gelation and postponed chemical reinforcing will provide a platform for 3D bioprinting applications.
展示了一种基于明胶和氧化葡聚糖相分离的、在生理pH范围内具有可调凝胶化时间的可挤出水凝胶。我们设想，这种水凝胶易于操作的特性与热敏物理凝胶化和延迟化学增强相结合，将为3D生物打印应用提供一个平台。
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