Kalsi Harpreet, McParland Helen, Cook Richard J
Dent Update. 2016 May;43(4):353-5. doi: 10.12968/denu.2016.43.4.353.
Sarcoidosis is a multisystem, non-caseating, chronic, granulomatous disease affecting any organ. In the head and neck region, salivary glands and lymph nodes are most commonly involved. Oral manifestations are rare but these lesions, occasionally haemorrhagic, may be the first sign of systemic disease. It is important to recognize the oral manifestations of sarcoidosis and to be aware of potential secondary disease-driven processes, such as thrombocytopenia. The purpose of this paper is to present a previously undiagnosed case of sarcoidosis, initially presenting with oral manifestations, including mucosal bleeding, and to review the current literature on oral sarcoidosis. Clinical relevance: Oral lesions can be the first sign of undiagnosed systemic sarcoidosis.
结节病是一种累及多系统、非干酪样、慢性、肉芽肿性疾病,可影响任何器官。在头颈部区域,唾液腺和淋巴结最常受累。口腔表现较为罕见,但这些病变偶尔会出血,可能是全身性疾病的首发症状。认识结节病的口腔表现并了解潜在的继发于疾病的过程,如血小板减少症,很重要。本文的目的是介绍一例先前未诊断出的结节病病例,该病例最初表现为口腔症状,包括黏膜出血,并回顾目前关于口腔结节病的文献。临床意义:口腔病变可能是未诊断出的全身性结节病的首发症状。