Bagchi Sudeshna, Shah Neha, Sheikh Mahmud Abdul, Chatterjee Rudra Prasad
Oral Pathology, Guru Nanak Institute of Dental Science and Research, Kolkata, India.
Oral Pathology, Guru Nanak Institute of Dental Science and Research, Kolkata, India
BMJ Case Rep. 2019 Dec 1;12(11):e232093. doi: 10.1136/bcr-2019-232093.
Sarcoidosis is a chronic, multisystemic, granulomatous disease of unknown aetiology characterised by the formation of non-caseating granuloma. It shows slight female predominance and has a bimodal age distribution. Lungs, skin, eye and liver are commonly affected. The oral lesion, though uncommon, may present as submucosal nodule, papule or superficial ulceration. Occasionally, oral lesion may be the first manifestation of underlying systemic disease. This case is interesting because it emphasises that dental practitioners may play a key role in early recognition of the clinical presentation of this multifaceted disease, and thereby aid in the diagnosis of the systemic condition. The present report deals with a case of sarcoidosis affecting the buccal mucosa in a 48-year-old woman. The patient was treated with oral prednisolone and within 4 months of corticosteroid therapy, the oral lesion regressed with no recurrence or new lesion noted over a period of 1 year.
结节病是一种病因不明的慢性、多系统、肉芽肿性疾病，其特征是形成非干酪样肉芽肿。该病女性略占优势，具有双峰年龄分布。肺、皮肤、眼睛和肝脏是常见受累部位。口腔病变虽不常见，但可表现为黏膜下结节、丘疹或浅表溃疡。偶尔，口腔病变可能是潜在全身性疾病的首发表现。该病例很有意思，因为它强调牙科医生在早期识别这种多方面疾病的临床表现中可能发挥关键作用，从而有助于全身性疾病的诊断。本报告涉及一名48岁女性患结节病累及颊黏膜的病例。患者接受口服泼尼松龙治疗，在皮质类固醇治疗的4个月内，口腔病变消退，在1年期间未发现复发或新病变。
