• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

白细胞淤滞:预防急性白血病危机的管理措施

Leukostasis: Management to Prevent Crisis in Acute Leukemia
.

作者信息

Blackburn Lisa M, Brown Shelly, Munyon Aimee, Orovets Michelle

机构信息

Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

出版信息

Clin J Oncol Nurs. 2017 Dec 1;21(6):E267-E271. doi: 10.1188/17.CJON.E267-E271.

DOI:10.1188/17.CJON.E267-E271
PMID:29149122
Abstract

BACKGROUND

Hyperleukocytosis, a peripheral white blood cell count greater than 100,000/mm3,is most commonly seen in patients with newly diagnosed or relapsed acute lymphoblastic leukemia and acute myeloid leukemia. Leukostasis is a reduction in blood flow related to hyperviscosity. Hyperleukocytosis, causing leukostasis, is an oncologic emergency and requires an exacting assessment and rapid response with appropriate intervention to prevent morbidity and mortality in the first week after diagnosis.

OBJECTIVES

The objectives of this article are to equip oncology nurse to identify patients with hyperleukocytosis and to provide nursing interventions that will ensure safe, quality care.

METHODS: A case study is used to demonstrate key concepts that are critical in early assessment, identification, and treatment of patients with leukostasis.
.

FINDINGS

Oncology nurses well versed in the pathophysiology, clinical presentation, and management of leukostasis can make a significant contribution to the safe management of patients with cancer.

摘要

背景

白细胞增多症是指外周血白细胞计数大于100,000/mm³,最常见于新诊断或复发的急性淋巴细胞白血病和急性髓细胞白血病患者。白细胞淤滞是指与血液高黏滞度相关的血流减少。导致白细胞淤滞的白细胞增多症是一种肿瘤急症,需要进行严格评估并迅速做出反应,采取适当干预措施以预防诊断后第一周内的发病和死亡。

目的

本文的目的是使肿瘤护理人员能够识别白细胞增多症患者,并提供能确保安全、优质护理的护理干预措施。

方法

采用案例研究来阐述在白细胞淤滞患者的早期评估、识别和治疗中至关重要的关键概念。

研究结果

精通白细胞淤滞病理生理学、临床表现和管理的肿瘤护理人员可为癌症患者的安全管理做出重大贡献。

相似文献

1
Leukostasis: Management to Prevent Crisis in Acute Leukemia
.白细胞淤滞:预防急性白血病危机的管理措施
Clin J Oncol Nurs. 2017 Dec 1;21(6):E267-E271. doi: 10.1188/17.CJON.E267-E271.
2
Acute leukemia with a very high leukocyte count: confronting a medical emergency.白细胞计数极高的急性白血病:应对医疗急症。
Cleve Clin J Med. 2004 Aug;71(8):633-7. doi: 10.3949/ccjm.71.8.633.
3
The effect of therapeutic leukapheresis on early complications and outcomes in patients with acute leukemia and hyperleukocytosis: a propensity score-matched study.治疗性白细胞单采术对急性白血病合并高白细胞血症患者早期并发症及预后的影响:一项倾向评分匹配研究
Transfusion. 2018 Jan;58(1):208-216. doi: 10.1111/trf.14329. Epub 2017 Sep 28.
4
Exchange Transfusion and Leukapheresis in Pediatric Patients with AML With High Risk of Early Death by Bleeding and Leukostasis.急性髓系白血病小儿患者早期因出血和白细胞淤滞死亡风险高时的换血疗法和白细胞去除术
Pediatr Blood Cancer. 2016 Apr;63(4):640-5. doi: 10.1002/pbc.25855. Epub 2015 Dec 16.
5
A rare complication of leukostasis with AML M4 patient: Microcirculatory dysfunction of upper extremities.AML M4 患者白细胞淤滞症的一种罕见并发症:上肢微循环功能障碍。
Transfus Apher Sci. 2023 Aug;62(4):103717. doi: 10.1016/j.transci.2023.103717. Epub 2023 May 2.
6
Hyperleukocytosis in Acute Myeloid Leukemia: Considerations for Inpatient Diagnosis and Management.急性髓系白血病中的高白细胞血症:住院诊断和管理的注意事项。
Clin J Oncol Nurs. 2023 Nov 16;27(6):589-593. doi: 10.1188/23.CJON.589-593.
7
Hyperleukocytosis and leukostasis in acute and chronic leukemias.急、慢性白血病中的高白细胞血症和白细胞淤滞症。
Leuk Lymphoma. 2022 Aug;63(8):1780-1791. doi: 10.1080/10428194.2022.2056178. Epub 2022 Mar 31.
8
Leukapheresis and exchange transfusion in children with acute leukemia and hyperleukocytosis. A single center experience.急性白血病合并高白细胞血症患儿的白细胞去除术和换血疗法。单中心经验。
Klin Padiatr. 2009 Nov-Dec;221(6):374-8. doi: 10.1055/s-0029-1239533. Epub 2009 Nov 4.
9
Hyperleukocytosis and Leukostasis in Acute Myeloid Leukemia: Can a Better Understanding of the Underlying Molecular Pathophysiology Lead to Novel Treatments?急性髓系白血病中的高白细胞血症和白细胞淤滞症:对潜在分子病理生理学的更好理解能否带来新的治疗方法?
Cells. 2020 Oct 17;9(10):2310. doi: 10.3390/cells9102310.
10
Rapid Fire: Acute Blast Crisis/Hyperviscosity Syndrome.速射:急性原始细胞危象/高黏滞综合征。
Emerg Med Clin North Am. 2018 Aug;36(3):603-608. doi: 10.1016/j.emc.2018.04.005. Epub 2018 Jun 11.

引用本文的文献

1
Emergencies in Hematology: Why, When and How I Treat?血液学急症:为何、何时以及如何进行治疗?
J Clin Med. 2024 Dec 12;13(24):7572. doi: 10.3390/jcm13247572.
2
Peer support-based online education, burden of care and quality of life among family caregivers of patients with leukaemia: non-randomised clinical trial.基于同伴支持的在线教育、白血病患者家庭照顾者的护理负担和生活质量:非随机临床试验
BMJ Support Palliat Care. 2024 Dec 19;14(e3):e2827-e2835. doi: 10.1136/spcare-2023-004610.
3
The Effect of Family-Centered Supportive Program on Chemotherapy-Induced Symptoms in Patients with Acute Lymphoblastic Leukemia (ALL).
以家庭为中心的支持项目对急性淋巴细胞白血病(ALL)患者化疗所致症状的影响
Int J Hematol Oncol Stem Cell Res. 2021 Jan 1;15(1):35-50. doi: 10.18502/ijhoscr.v15i1.5248.
4
Leukostasis in Chronic Lymphocytic Leukemia.慢性淋巴细胞白血病中的白细胞淤滞。
Am J Case Rep. 2020 Jul 3;21:e924798. doi: 10.12659/AJCR.924798.