Department of Psychology, Seoul National University, Seoul, South Korea.
Depression Center, Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
J Affect Disord. 2018 Feb;227:384-390. doi: 10.1016/j.jad.2017.11.008. Epub 2017 Nov 6.
To date, shortened versions of the Hypomania Checklist-32 (HCL-32) were proposed to overcome the limitation of a lengthy format; however, a cross-validation study is currently needed to identify which shorter version may function optimally in a clinical sample.
In a Korean patient sample with bipolar disorder (BD) and major depressive disorder (MDD) (BD-I n = 84, BD = II n = 145, MDD n = 285), we examined the reliability and screening property of three shorter versions of the HCL (HCL-20, -16, -8) in comparison with the full HCL-32. Diagnosis was confirmed by the structured clinical interview (SCID-I).
All three shortened HCLs demonstrated a fair screening ability (Area Under the Curve = .72~.74) to discriminate BD patients from MDD patients, which was comparable to that of the HCL-32. When sensitivity and specificity were considered, the HCL-20 showed relatively superior performance among the shortened versions.
The shorter versions were not administered in a 'stand-alone' manner.
This is the first cross-validation study in a large clinical sample with an increased statistical power to compare the screening property of the shortened HCLs. Our results suggest that briefer versions of the HCL could be reliably and economically utilized in clinical and research settings to enhance detection of BD.
迄今为止，为了克服冗长格式的限制，已经提出了短版的躁狂检查表-32（HCL-32）；然而，目前仍需要进行交叉验证研究，以确定哪种较短的版本在临床样本中可能表现最佳。
在一个有双相情感障碍（BD）和重度抑郁症（MDD）的韩国患者样本中（BD-I 组 n = 84，BD-II 组 n = 145，MDD 组 n = 285），我们比较了 HCL 的三个较短版本（HCL-20、-16、-8）与完整的 HCL-32 的可靠性和筛选特性。诊断通过结构临床访谈（SCID-I）确认。
所有三种缩短的 HCL 都表现出良好的筛选能力（曲线下面积 =.72~.74），能够区分 BD 患者和 MDD 患者，与 HCL-32 相当。当考虑灵敏度和特异性时，HCL-20 在缩短版本中表现出相对较好的性能。
缩短版本并非以“独立”的方式进行管理。
这是第一项在大临床样本中进行的交叉验证研究，其统计效力增加，可比较缩短的 HCL 筛选特性。我们的结果表明，在临床和研究环境中，可以可靠且经济地使用 HCL 的简短版本，以增强对 BD 的检测。
