莪术的临床疗效：一项系统评价。
Clinical effects of Zingiber cassumunar (Plai): A systematic review.
作者信息
Chongmelaxme Bunchai, Sruamsiri Rosarin, Dilokthornsakul Piyameth, Dhippayom Teerapon, Kongkaew Chuenjid, Saokaew Surasak, Chuthaputti Anchalee, Chaiyakunapruk Nathorn
机构信息
Center of Pharmaceutical Outcomes Research, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.
Center of Pharmaceutical Outcomes Research, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.
出版信息
Complement Ther Med. 2017 Dec;35:70-77. doi: 10.1016/j.ctim.2017.09.009. Epub 2017 Oct 7.
Zingiber cassumunar Roxb. known locally as "Plai" in Thai, has been used for treating bruise, sprain and musculoskeletal pain. Several pre-clinical studies demonstrated the anti-inflammatory effect of Plai. However, current evidence of clinical effects of Plai is still unclear. This study aimed to determine the clinical efficacy and safety of Plai among all identified indications. Of the 808 articles identified by a systematic review, six studies were included. Four studies were randomized controlled trials, while two studies were quasi-experimental studies involving 178 patients in intervention group and 177 patients in control group. Duration of treatment ranged from 7days to 2 months. Our findings showed that 14% Plai cream had a strong trend of benefits in pain reduction for muscle pain and ankle sprain. However, evidence supporting the effects of Plai on acne vulgaris treatment and anti-histamine effect are still unclear.
泰国当地称为“Plai”的高良姜已被用于治疗瘀伤、扭伤和肌肉骨骼疼痛。多项临床前研究证明了Plai的抗炎作用。然而，目前关于Plai临床效果的证据仍不明确。本研究旨在确定Plai在所有已确定适应症中的临床疗效和安全性。在系统评价确定的808篇文章中，纳入了6项研究。4项研究为随机对照试验，2项研究为准实验研究，干预组有178例患者，对照组有177例患者。治疗持续时间为7天至2个月。我们的研究结果表明，14%的Plai乳膏在减轻肌肉疼痛和脚踝扭伤疼痛方面有显著的益处趋势。然而，支持Plai治疗寻常痤疮和抗组胺作用的证据仍不明确。
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