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对1123例连续的颈椎前路椎间盘切除融合术病例进行的单外科医生回顾性研究:门诊手术组与住院手术组临床结果参数、并发症发生率及费用的比较,并附文献综述

Retrospective single-surgeon study of 1123 consecutive cases of anterior cervical discectomy and fusion: a comparison of clinical outcome parameters, complication rates, and costs between outpatient and inpatient surgery groups, with a literature review.

作者信息

Mullins Jack, Pojskić Mirza, Boop Frederick A, Arnautović Kenan I

机构信息

1College of William & Mary, Williamsburg, Virginia.

2Department of Neurosurgery, University of Marburg, Germany.

出版信息

J Neurosurg Spine. 2018 Jun;28(6):630-641. doi: 10.3171/2017.10.SPINE17938. Epub 2018 Mar 30.

Abstract

OBJECTIVE Outpatient anterior cervical discectomy and fusion (ACDF) is becoming more common and has been reported to offer advantages over inpatient procedures, including reducing nosocomial infections and costs, as well as improving patient satisfaction. The goal of this retrospective study was to evaluate and compare outcome parameters, complication rates, and costs between inpatient and outpatient ACDF cases performed by 1 surgeon at a single institution. METHODS In a retrospective study, the records of all patients who had undergone first-time ACDF performed by a single surgeon in the period from June 1, 2003, to January 31, 2016, were reviewed. Patients were categorized into 2 groups: those who had undergone ACDF as outpatients in a same-day surgical center and those who had undergone surgery in the hospital with a minimum 1-night stay. Outcomes for all patients were evaluated with respect to the following parameters: age, sex, length of stay, preoperative and postoperative pain (self-reported questionnaires), number of levels fused, fusion, and complications, as well as the presence of risk factors, such as an increased body mass index, smoking, and diabetes mellitus. RESULTS In total, 1123 patients were operated on, 485 (43%) men and 638 (57%) women, whose mean age was 50 years. The mean follow-up time was 25 months. Overall, 40.5% underwent 1-level surgery, 34.3% 2-level, 21.9% 3-level, and 3.2% 4-level. Only 5 patients had nonunion of vertebrae; thus, the fusion rate was 99.6%. Complications occurred in 40 patients (3.6%), with 9 having significant complications (0.8%). Five hundred sixty patients (49.9%) had same-day surgery, and 563 patients (50.1%) stayed overnight in the hospital. The inpatients were older, were more commonly male, and had a higher rate of diabetes. Smoking status did not influence the length of stay. Both groups had a statistically significant reduction in pain (expressed as a visual analog scale score) postoperatively with no significant difference between the groups. One- and 2-level surgeries were done significantly more often in the outpatient setting (p < 0.001). The complication rate was 4.1% in the outpatient group and 3.0% in the inpatient group; there was no statistically significant difference between the 2 groups (p = 0.339). Significantly more complications occurred with 3- and 4-level surgeries than with 1- and 2-level procedures (p < 0.001, chi-square test). The overall average inpatient cost for commercial insurance carriers was 26% higher than those for outpatient surgery. CONCLUSIONS Anterior cervical discectomy and fusion is safe for patients undergoing 1- or 2-level surgery, with a very significant rate of pain reduction and fusion and a low complication rate in both clinical settings. Outpatient and inpatient groups undergoing 3- or 4-level surgery had an increased risk of complications (compared with those undergoing 1- or 2-level surgery), with a negligible difference between the 2 groups. This finding suggests that these procedures can also be included as standard outpatient surgery. Comparable outcome parameters and the same complication rates between inpatient and outpatient groups support both operative environments.

摘要

目的 门诊前路颈椎间盘切除融合术(ACDF)越来越普遍,据报道与住院手术相比具有诸多优势,包括减少医院感染和费用,以及提高患者满意度。本回顾性研究的目的是评估和比较由一名外科医生在单一机构进行的住院和门诊ACDF病例的结果参数、并发症发生率和费用。方法 在一项回顾性研究中,对2003年6月1日至2016年1月31日期间由一名外科医生进行首次ACDF的所有患者的记录进行了审查。患者分为两组:在同日手术中心接受门诊ACDF的患者和在医院至少住院一晚的患者。对所有患者的以下参数进行了评估:年龄、性别、住院时间、术前和术后疼痛(自我报告问卷)、融合节段数、融合情况和并发症,以及危险因素的存在情况,如体重指数增加、吸烟和糖尿病。结果 总共对1123例患者进行了手术,其中485例(43%)为男性,638例(57%)为女性,平均年龄为50岁。平均随访时间为25个月。总体而言,40.5%的患者接受了单节段手术,34.3%为双节段,21.9%为三节段,3.2%为四节段。只有5例患者出现椎体不融合;因此,融合率为99.6%。40例患者(3.6%)发生了并发症,其中9例出现严重并发症(0.8%)。560例患者(49.9%)进行了同日手术,563例患者(50.1%)在医院过夜。住院患者年龄较大,男性更常见,糖尿病发生率更高。吸烟状况不影响住院时间。两组患者术后疼痛(以视觉模拟量表评分表示)均有统计学意义的降低,两组之间无显著差异。单节段和双节段手术在门诊环境中进行的频率明显更高(p < 0.001)。门诊组并发症发生率为4.1%,住院组为3.0%;两组之间无统计学显著差异(p = 0.339)。三节段和四节段手术的并发症明显多于单节段和双节段手术(p < 0.001,卡方检验)。商业保险公司的住院总体平均费用比门诊手术高26%。结论 前路颈椎间盘切除融合术对于接受单节段或双节段手术的患者是安全的,在两种临床环境中疼痛减轻和融合率非常显著,并发症发生率低。接受三节段或四节段手术的门诊和住院组并发症风险增加(与接受单节段或双节段手术的患者相比),两组之间差异可忽略不计。这一发现表明这些手术也可作为标准门诊手术。住院和门诊组之间可比的结果参数和相同的并发症发生率支持两种手术环境。

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