Emerg Infect Dis. 2017 Oct;23(13):S47-52. doi: 10.3201/eid2313.170443.
Monitoring trends in antimicrobial drug-resistant Neisseria gonorrhoeae is a critical public health and global health security activity because the number of antimicrobial drugs available to treat gonorrhea effectively is rapidly diminishing. Current global surveillance methods for antimicrobial drug-resistant N. gonorrhoeae have many limitations, especially in countries with the greatest burden of disease. The Enhanced Gonococcal Antimicrobial Surveillance Program is a collaboration between the World Health Organization and the Centers for Disease Control and Prevention. The program aims to monitor trends in antimicrobial drug susceptibilities in N. gonorrhoeae by using standardized sampling and laboratory protocols; to improve the quality, comparability, and timeliness of gonococcal antimicrobial drug resistance data across multiple countries; and to assess resistance patterns in key populations at highest risk for antimicrobial drug-resistant gonorrhea so country-specific treatment guidelines can be informed.
监测耐抗生素淋病奈瑟菌的趋势是一项至关重要的公共卫生和全球卫生安全活动,因为可有效治疗淋病的抗生素药物数量正在迅速减少。目前针对耐抗生素淋病奈瑟菌的全球监测方法存在诸多局限性,在疾病负担最大的国家尤其如此。强化淋球菌抗生素监测计划是世界卫生组织和疾病预防控制中心之间的一项合作。该计划旨在通过使用标准化的抽样和实验室方案来监测淋病奈瑟菌对抗生素药物敏感性的趋势;提高多个国家淋病奈瑟菌抗抗生素药物耐药性数据的质量、可比性和及时性;评估高危人群中的耐药模式,以便为制定特定国家的治疗指南提供信息。