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胃重复囊肿起源的腺癌:一例报告及文献复习

Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review.

作者信息

Abdulla Maheeba Abdulla Mohamed, Al Saeed Mahmood, Ameer Alshaikh Safa, Nabar Umesh J

机构信息

Department of Internal Medicine.

Department of Pathology.

出版信息

Int Med Case Rep J. 2017 Nov 6;10:367-372. doi: 10.2147/IMCRJ.S138616. eCollection 2017.

DOI:10.2147/IMCRJ.S138616
PMID:29158693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5683793/
Abstract

INTRODUCTION

Alimentary tract cystic duplication is a rare congenital anomaly predominantly affecting females, and diagnosed mostly in the early years of life.

CASE REPORT

We present here a case of a 51-year-old man presenting with a 2-day history of melena. Gastroscopy showed fresh blood, as well as a mass lesion and cavity at the fundus. Biopsies of the mass edge reported the occurrence of moderately differentiated adenocarcinoma and mild chronic gastritis. Computed tomography imaging showed a 5.1×6.5 cm cystic mass in the gastric greater curvature. The patient received six cycles of epirubicin, capecitabine, and oxaliplatin, followed by uncomplicated total gastrectomy.

LITERATURE REVIEW

Data from all 11 reports of similar cases were reviewed and pooled. The result shows male predominance and variable symptoms, as well as a wide age range (25-76 years) at presentation. The cysts are commonly located along the greater curvature and are unilocular. Surgery was the treatment in most cases.

CONCLUSION

Alimentary tract cystic duplication is rare and may predispose to malignancy. Early diagnosis and prompt surgical intervention is important for the best outcome.

摘要

引言

消化道囊肿性重复畸形是一种罕见的先天性异常,主要影响女性,大多在生命早期被诊断出来。

病例报告

我们在此呈现一例51岁男性,有2天的黑便病史。胃镜检查显示有新鲜血液,以及胃底的肿块病变和空洞。肿块边缘活检报告为中分化腺癌和轻度慢性胃炎。计算机断层扫描成像显示胃大弯处有一个5.1×6.5厘米的囊性肿块。患者接受了六个周期的表柔比星、卡培他滨和奥沙利铂治疗,随后进行了无并发症的全胃切除术。

文献综述

对所有11篇类似病例报告的数据进行了回顾和汇总。结果显示男性居多,症状多样,发病年龄范围广泛(25 - 76岁)。囊肿通常位于大弯处,为单房性。大多数病例采用手术治疗。

结论

消化道囊肿性重复畸形罕见,可能易引发恶性肿瘤。早期诊断和及时的手术干预对于获得最佳治疗效果很重要。

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