起源于胃重复囊肿并侵犯胃的腺癌：一例报告并文献复习
Adenocarcinoma arising from a gastric duplication cyst with invasion to the stomach: a case report with literature review.
作者信息
Kuraoka K, Nakayama H, Kagawa T, Ichikawa T, Yasui W
机构信息
Department of Molecular Pathology, Hiroshima University Graduate School of Biomedical Sciences, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
出版信息
J Clin Pathol. 2004 Apr;57(4):428-31. doi: 10.1136/jcp.2003.013946.
This report describes a rare case of adenocarcinoma arising from a gastric duplication cyst, with invasion to the stomach wall, in a 40 year old Japanese man. A cystic lesion was found between the stomach and the spleen. The cyst had a well circumscribed smooth muscle layer, corresponding to the muscularis propria of the stomach and the mucosa of the alimentary tract. A well differentiated adenocarcinoma was found within the duplication cyst, invading its serosa. Well differentiated adenocarcinoma was independently found in the fundus of the stomach; the tumour of the cyst was connected by fibrous tissue. Microscopically, there was neither adenocarcinoma in situ nor precancerous lesions, such as epithelial dysplasia, suggesting that the carcinoma derived from a gastric duplication cyst that invaded the stomach. Duplication cysts should be included in the differential diagnosis of cystic masses of the gastrointestinal tract, and the possibility of malignancy within these cysts should be considered.
本报告描述了一名40岁日本男性中罕见的起源于胃重复囊肿并侵犯胃壁的腺癌病例。在胃和脾脏之间发现了一个囊性病变。该囊肿有界限清楚的平滑肌层，对应于胃的固有肌层和消化道的黏膜。在重复囊肿内发现了高分化腺癌，侵犯了其浆膜。在胃底独立发现了高分化腺癌；囊肿的肿瘤通过纤维组织相连。显微镜下，既没有原位腺癌也没有上皮发育异常等癌前病变，提示该癌源自侵犯胃的胃重复囊肿。重复囊肿应纳入胃肠道囊性肿块的鉴别诊断中，并应考虑这些囊肿内发生恶性肿瘤的可能性。
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