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神经毒剂(沙林、塔崩和VX)的高选择性和灵敏显色检测:一种多分析物检测方法。

Highly selective and sensitive chromogenic detection of nerve agents (sarin, tabun and VX): a multianalyte detection approach.

作者信息

Kumar Vinod, Raviraju G, Rana Hemlata, Rao Vepa Kameswara, Gupta Arvind K

机构信息

Defence Research & Development Establishment, Jhansi Road, Gwalior 474002, India.

出版信息

Chem Commun (Camb). 2017 Nov 30;53(96):12954-12957. doi: 10.1039/c7cc07823d.

DOI:10.1039/c7cc07823d
PMID:29159359
Abstract

A novel strategy using ferrocenyl dye (1) was developed for highly selective chromogenic detection of all nerve agents. The protocol was first established with nerve agent mimics (DFP, DCNP, and malaoxon) and then implemented on real agents, i.e. sarin, tabun and VX. The developed chemosensor showed no interferences from the most probable interferents such as acetyl chloride, sulfur mustard, oxygen mustard and DMMP. Real-time visual detection with a lower limit of detection (below LD) made the present protocol highly appealing and versatile.

摘要

开发了一种使用二茂铁基染料(1)的新策略,用于对所有神经毒剂进行高选择性显色检测。该方案首先用神经毒剂模拟物(DFP、DCNP和马拉氧磷)建立,然后应用于实际毒剂,即沙林、塔崩和VX。所开发的化学传感器不受最可能的干扰物如乙酰氯、硫芥、氧芥和DMMP的干扰。具有较低检测限(低于LD)的实时视觉检测使本方案极具吸引力且用途广泛。

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