Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio.
Department of Internal Medicine, NYU Langone Health, New York, New York.
JAMA Intern Med. 2018 Jan 1;178(1):116-122. doi: 10.1001/jamainternmed.2017.6369.
Although blood transfusion is a lifesaving therapy for some patients, transfusion has been named 1 of the top 5 overused procedures in US hospitals. As unnecessary transfusions only increase risk and cost without providing benefit, improving transfusion practice is an effective way of promoting high-value care. Most high-quality clinical trials supporting a restrictive transfusion strategy have been published in the past 5 to 10 years, so the value of a successful patient blood management program has only recently been recognized. We review the most recent transfusion practice guidelines and the evidence supporting these guidelines. We also discuss several medical societies' Choosing Wisely campaigns to reduce or eliminate overuse of transfusions. A blueprint is presented for developing a patient blood management program, which includes discussion of specific methods for optimizing transfusion practice.
尽管输血是一些患者的救命疗法,但输血已被命名为美国医院中过度使用的前 5 大程序之一。由于不必要的输血只会增加风险和成本而没有带来益处,因此改善输血实践是促进高价值护理的有效方法。大多数支持限制性输血策略的高质量临床试验都是在过去 5 到 10 年内发表的,因此成功的患者血液管理计划的价值直到最近才得到认可。我们回顾了最新的输血实践指南以及支持这些指南的证据。我们还讨论了几个医学协会的“明智选择”活动,以减少或消除输血的过度使用。提出了制定患者血液管理计划的蓝图,其中包括讨论优化输血实践的具体方法。