Food Toxicology Laboratory, Food, Drug and Chemical Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), 31, Vishvigyan Bhawan, P.O. Box No. 80, Mahatma Gandhi Marg, Lucknow, Uttar Pradesh, 226 001, India.
Academy of Scientific and Innovative Research (AcSIR), CSIR-IITR, Lucknow, India.
Clin Rev Allergy Immunol. 2019 Aug;57(1):39-54. doi: 10.1007/s12016-017-8651-2.
Mustard is widely used in a variety of foods/food products to enhance the flavor and nutritional value that subsequently raise the risk of hypersensitivity reactions. Mustard allergy has been reported for many years and is increasing gradually especially in the areas where its consumption is comparatively higher, and it may be considered among the most important food allergies. A number of relevant clinical studies focused on mustard-induced allergic manifestations are summarized in the current review. In addition, the knowledge regarding the immunological as well as biochemical characteristics of mustard allergens that have been known till date and their cross-reactivity with other food allergens have also been discussed here. Notably, mustard may also be present as a hidden allergen in foods; therefore, it is important to recognize food products that may contain mustard as it may pose potential risk for the allergic individuals. Additionally, the better understanding of the underlying mechanism in mustard allergy is a prerequisite for the development of specific therapeutic procedures. Conclusively, mustard sensitivity should be routinely tested in patients with idiopathic anaphylaxis for the safety of the allergic patients.
芥菜广泛用于各种食品/食品产品中，以提高风味和营养价值，从而增加过敏反应的风险。多年来一直有芥菜过敏的报道，而且这种情况在芥菜消费相对较高的地区逐渐增加，它可能被认为是最重要的食物过敏之一。目前的综述总结了一些相关的临床研究，这些研究集中在芥菜引起的过敏表现上。此外，本文还讨论了芥菜过敏原的免疫学和生物化学特性以及它们与其他食物过敏原的交叉反应性，这些知识到目前为止已经为人所知。值得注意的是，芥菜也可能作为一种隐藏的过敏原存在于食物中；因此，识别可能含有芥菜的食品非常重要，因为这可能对过敏个体构成潜在风险。此外，更好地了解芥菜过敏的潜在机制是开发特异性治疗程序的前提。总之，为了过敏患者的安全，应在特发性过敏反应患者中常规检测芥菜敏感性。
