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SEOM 头颈部肿瘤临床治疗指南（2017 年）

SEOM clinical guidelines for the treatment of head and neck cancer (2017).

机构信息

Hospital Universitario 12 de Octubre, Madrid, Spain.

Hospital de Basurto, Bilbao, Spain.

出版信息

Clin Transl Oncol. 2018 Jan;20(1):75-83. doi: 10.1007/s12094-017-1776-1. Epub 2017 Nov 20.

DOI:10.1007/s12094-017-1776-1
PMID:29159792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5785598/
Abstract

Head and neck cancer (HNC) is defined as malignant tumours located in the upper aerodigestive tract and represents 5% of oncologic cases in adults in Spain. More than 90% of these tumours have squamous histology. In an effort to incorporate evidence obtained since 2013 publication, Spanish Society of Medical Oncology (SEOM) presents an update of HNC diagnosis and treatment guideline. The eighth edition of TNM classification, published in January 2017, introduces important changes for p16-positive oropharyngeal tumours, for lip and oral cavity cancer and for N3 category. In addition, there are new data about induction chemotherapy and the role of immunotherapy in HNC.

摘要

头颈部癌（HNC）定义为位于上呼吸道消化道的恶性肿瘤，占西班牙成人肿瘤病例的 5%。这些肿瘤中超过 90%具有鳞状组织学。为了纳入自 2013 年出版以来获得的证据，西班牙肿瘤医学学会（SEOM）提出了头颈部癌诊断和治疗指南的更新。2017 年 1 月公布的第 8 版 TNM 分类对 p16 阳性口咽肿瘤、唇癌和口腔癌以及 N3 类别的分类引入了重要变化。此外，还有关于诱导化疗和免疫疗法在头颈部癌中的新数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ed2/5785598/0716c5a69ba6/12094_2017_1776_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ed2/5785598/4be090e6801b/12094_2017_1776_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ed2/5785598/b4bc021d2d65/12094_2017_1776_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ed2/5785598/0716c5a69ba6/12094_2017_1776_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ed2/5785598/4be090e6801b/12094_2017_1776_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ed2/5785598/b4bc021d2d65/12094_2017_1776_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ed2/5785598/0716c5a69ba6/12094_2017_1776_Fig3_HTML.jpg

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Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort.
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莱姆叶的抗增殖和免疫调节特性及其与鳞状细胞癌细胞共培养的巨噬细胞的生物活性化合物。
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6-shogaol is a potential treatment for Head and Neck Squamous Cell Carcinoma.6-姜烯酚是头颈部鳞状细胞癌的一种潜在治疗方法。
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