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含氟涂料预防软饮料与小儿药水混合导致的牙齿侵蚀

Fluoride Varnishes against Dental Erosion Caused by Soft Drink Combined with Pediatric Liquid Medicine.

作者信息

Alexandria Adílis Kalina, Valença Ana Maria Gondim, Cabral Lúcio Mendes, Maia Lucianne Cople

机构信息

Department of Pediatric Dentistry and Orthodontics, Dental School, UFRJ - Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Department of Clinical and Social Dentistry, Dental School, UFPB - Universidade Federal da Paraiba, João Pessoa, PB, Brazil.

出版信息

Braz Dent J. 2017 Jul-Aug;28(4):482-488. doi: 10.1590/0103-6440201701567.

DOI:10.1590/0103-6440201701567
PMID:29160401
Abstract

The present study evaluated the effect of NaF and CPP-ACP/NaF varnishes to reduce erosion produced by soft drink (SD) combined or not with pediatric liquid medicine. Enamel specimens were pre-treated with fluoride varnish, according to the following groups: NaF varnish (Duraphat®) or CPP-ACP/NaF varnish (MI varnishTM). Two types of erosive cycles were made: by soft drink erosion (SDE) or by pediatric liquid medicine plus soft drink erosion (PLM/SDE). Bovine enamel specimens were randomly assigned in six groups (n=10): G1=NaF + SDE; G2=CPP-ACP/NaF + SDE; G3=Distilled and deionized (DD) water + SDE; G4=NaF + PLM/SDE; G5=CPP-ACP/NaF + PLM/SDE and G6=DD water + PLM/SDE. Before treatments, the sample surface was divided in two areas (unexposed area-UA and exposed area-EA). The specimens were evaluated by 3D non-contact profilometry technique to determinate tooth structure loss (TSL) and surface roughness (Sa). Scanning electron microscopy (SEM) analysis was also performed. After SDE, G2 presented the lowest TSL values compared to G3 (p=0.008). G1 and G2 did not differ between them (p=0.203) and no groups differed among them despite Sa. Regarding TSL and Sa, G4 and G5 differed from G6 (p=0.0001), but not between them (p=1.00). Examining 3D and SEM images, the greatest differences between UA and EA were observed for G3 and G6. CPP-ACP/NaF varnish seems to be a promising treatment to reduce enamel loss from the erosion produced by a soft drink. Both varnishes also showed capacity to reduce TSL and Sa after erosion by soft drink combined to pediatric liquid medicine.

摘要

本研究评估了氟化钠(NaF)和酪蛋白磷酸肽-无定形磷酸钙/氟化钠(CPP-ACP/NaF)清漆对减少由软饮料(SD)单独或与儿科液体药物联合产生的酸蚀的效果。根据以下分组,用氟化物清漆对牙釉质标本进行预处理:NaF清漆(Duraphat®)或CPP-ACP/NaF清漆(MI varnishTM)。进行了两种类型的酸蚀循环:通过软饮料酸蚀(SDE)或通过儿科液体药物加软饮料酸蚀(PLM/SDE)。将牛牙釉质标本随机分为六组(n = 10):G1 = NaF + SDE;G2 = CPP-ACP/NaF + SDE;G3 = 蒸馏水和去离子水(DD) + SDE;G4 = NaF + PLM/SDE;G5 = CPP-ACP/NaF + PLM/SDE和G6 = DD水 + PLM/SDE。在处理前,将样品表面分为两个区域(未暴露区域-UA和暴露区域-EA)。通过三维非接触轮廓测量技术对标本进行评估,以确定牙齿结构损失(TSL)和表面粗糙度(Sa)。还进行了扫描电子显微镜(SEM)分析。在SDE后,与G3相比,G2呈现出最低的TSL值(p = 0.008)。G1和G2之间无差异(p = 0.203),且就Sa而言,各组之间无差异。关于TSL和Sa,G4和G5与G6不同(p = 0.0001),但它们之间无差异(p = 1.00)。检查三维和SEM图像,在G3和G6中观察到UA和EA之间的最大差异。CPP-ACP/NaF清漆似乎是一种有前景的治疗方法,可减少软饮料产生的酸蚀对牙釉质的损失。两种清漆在软饮料与儿科液体药物联合酸蚀后也显示出减少TSL和Sa的能力。

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