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Cadmium and metallothionein levels in the liver of humans exposed to environmental cadmium in Upper Silesia, Poland.

作者信息

Bem E M, Piotrowski J K, Koziara H

机构信息

Department of Toxicological Chemistry, Medical Academy, Lodz, Poland.

出版信息

Toxicol Lett. 1989 Jan;45(1):35-9. doi: 10.1016/0378-4274(89)90156-2.

Abstract

The area of Upper Silesia is the most industrialized region in Poland. The concentrations of cadmium (Cd), zinc (Zn), copper (Cu) and metallothionein (MT) in autopsy samples (n = 29) of liver from the inhabitants of that area were determined. The metal levels varied in the ranges of 0.5-11.9 micrograms Cd/g, 45.3-221.6 micrograms Zn/g, 1.4-10.3 micrograms Cu/g. The concentration of MT determined by the Hg-method was high: 0.38-2.86 mumol Hg/g. A positive linear relationship was observed between Zn and MT levels.

摘要

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