Choi Young-Hyun, Hong Jee-Young, Lee Moo-Sik
Department of Preventive Medicine and Public Health, College of Medicine, Konyang University, Daejeon, Korea.
Osong Public Health Res Perspect. 2017 Oct;8(5):358-366. doi: 10.24171/j.phrp.2017.8.5.10. Epub 2017 Oct 31.
This study aimed to analyze changes in hematologic parameters in the residents of the areas highly contaminated by the Hebei Spirit Oil Spill in 2007 and those who participated in the clean-up activities.
According to demographic characteristics, health status and behavior, and level of exposure to oil, we compared the hematologic results in 2009 and 2012 among 701 residents. The hematologic parameters were composed of white blood cell (WBC) count, and levels of hemoglobin, hematocrit (Hct), aspartate aminotransferase (AST), alanine aminotransferase (ALT), glucose, glycosylated hemoglobin (HbA1c), blood urea nitrogen (BUN), creatinine (Cr), total cholesterol (T-chol), high-density lipoprotein (HDL), and triglyceride (TG).
Paired -test revealed that the WBC count and levels of Hct, AST, ALT, glucose, and HbA1c significantly increased, whereas the BUN, Cr, HDL, and TG levels significantly decreased. Multiple linear regression modelling showed a relationship between the level of exposure to oil and temporal changes in Hct, glucose, HbA1c, and BUN levels.
Our results suggest a relationship between level of exposure to oil and changes in hematologic parameters over 3 years. Further studies should be conducted to determine the impact of oil spill on health such as the occurrence of diseases.
本研究旨在分析2007年受河北精神号油轮漏油事件高度污染地区居民以及参与清理活动居民的血液学参数变化。
根据人口统计学特征、健康状况与行为以及油污暴露水平，我们比较了701名居民在2009年和2012年的血液学检查结果。血液学参数包括白细胞（WBC）计数、血红蛋白水平、血细胞比容（Hct）、天冬氨酸转氨酶（AST）、丙氨酸转氨酶（ALT）、血糖、糖化血红蛋白（HbA1c）、血尿素氮（BUN）、肌酐（Cr）、总胆固醇（T-chol）、高密度脂蛋白（HDL）和甘油三酯（TG）。
配对t检验显示，白细胞计数、血细胞比容、AST、ALT、血糖和糖化血红蛋白水平显著升高，而血尿素氮、肌酐、高密度脂蛋白和甘油三酯水平显著降低。多元线性回归模型显示油污暴露水平与血细胞比容、血糖、糖化血红蛋白和血尿素氮水平的时间变化之间存在关联。
我们的结果表明油污暴露水平与3年内血液学参数变化之间存在关联。应开展进一步研究以确定漏油事件对健康的影响，如疾病的发生情况。
