Department of Radiation Oncology, College of Medicine, University of Florida.
Exerc Sport Sci Rev. 2018 Jan;46(1):56-64. doi: 10.1249/JES.0000000000000137.
An imbalance in oxygen delivery to demand in solid tumors results in local areas of hypoxia leading to poor prognosis for the patient. We hypothesize that aerobic exercise increases tumor blood flow, recruits previously nonperfused tumor blood vessels, and thereby augments blood-tumor O2 transport and diminishes tumor hypoxia. When combined with conventional anticancer treatments, aerobic exercise can significantly improve the outcomes for several types of cancers.
在实体瘤中，氧供与氧需之间的失衡会导致局部缺氧，从而导致患者预后不良。我们假设有氧运动可以增加肿瘤血流量，募集先前未灌注的肿瘤血管，从而增加血液-肿瘤氧气输送并减轻肿瘤缺氧。当与传统的抗癌治疗相结合时，有氧运动可以显著改善多种癌症的治疗效果。
