Ney J A, Fee S C, Dooley S L, Socol M L, Minogue J
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, IL.
Am J Obstet Gynecol. 1989 Feb;160(2):424-6. doi: 10.1016/0002-9378(89)90464-x.
Bleeding from the site of cordocentesis can be detected by ultrasound examination, but significant hemorrhage into the amniotic fluid rarely occurs. To evaluate the relative contribution of amniotic fluid thromboplastins and the quantity of Wharton's jelly in facilitating coagulation at the puncture site, amniotic fluid samples and umbilical cord segments were obtained at cesarean section from 20 patients. After puncture of the umbilical vein, bleeding times were measured in amniotic fluid and 0.9% sodium chloride. The quantity of Wharton's jelly was assessed by measuring umbilical cord circumference. Mean bleeding times were significantly shorter in amniotic fluid compared with saline solution, but there was no consistent relationship between bleeding times and umbilical cord circumference. We conclude that properties of amniotic fluid facilitate coagulation at the site of umbilical vein puncture.
超声检查可检测到脐带穿刺部位的出血，但羊水内大量出血很少发生。为评估羊水凝血活酶的相对作用以及华通胶的量对穿刺部位凝血的促进作用，在剖宫产时从20例患者获取羊水样本和脐带段。穿刺脐静脉后，测量羊水和0.9%氯化钠溶液中的出血时间。通过测量脐带周长评估华通胶的量。与盐溶液相比，羊水内的平均出血时间显著缩短，但出血时间与脐带周长之间无一致关系。我们得出结论，羊水的特性有助于脐静脉穿刺部位的凝血。
