Solodovnik Daria A, Tatonova Yulia V, Burkovskaya Polina V
Far Eastern Federal University, School of Natural Sciences, Sukhanova Street, 8, Vladivostok, 690090, Russia.
Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far Eastern Branch, Russian Academy of Sciences, 100-letiya Street, 159, Vladivostok, 690022, Russia.
Parasitol Res. 2018 Jan;117(1):335-338. doi: 10.1007/s00436-017-5687-4. Epub 2017 Nov 22.
Clonorchis sinensis, the causative agent of clonorchiasis, is one of the most important parasites that inhabit countries of East and Southeast Asia. In this study, we validated the existence of a geographical vector for C. sinensis using the partial cox1 mtDNA gene, which includes a conserved region. The samples of parasite were divided into groups corresponding to three river basins, and the size of the conserved region had a strong tendency to increase from the northernmost to the southernmost samples. This indicates the availability of the geographical vector in distribution of genetic diversity. A vector is a quantity that is characterized by magnitude and direction. Geographical vector obtained in cox1 gene of C. sinensis has both these features. The reasons for the occurrence of this feature, including the influence of intermediate and definitive hosts on vector formation, and the possibility of its use for clonorchiasis monitoring are discussed. Graphical abstract ᅟ.
华支睾吸虫是华支睾吸虫病的病原体，是栖息在东亚和东南亚国家的最重要寄生虫之一。在本研究中，我们使用包含保守区域的部分细胞色素氧化酶亚基1（cox1）线粒体DNA基因验证了华支睾吸虫地理载体的存在。将寄生虫样本分为对应于三个流域的组，保守区域的大小有从最北端样本到最南端样本强烈增加的趋势。这表明地理载体在遗传多样性分布中的可用性。载体是一种具有大小和方向特征的量。在华支睾吸虫的cox1基因中获得的地理载体具有这两个特征。讨论了出现此特征的原因，包括中间宿主和终末宿主对载体形成的影响，以及将其用于华支睾吸虫病监测的可能性。图形摘要ᅟ
