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成年人自闭症谱系障碍患者与非自闭症谱系障碍患者在视觉阻断后的姿势和皮质反应。

Postural and Cortical Responses Following Visual Occlusion in Adults With and Without ASD.

机构信息

Faculty of Science and Engineering, Curtin University, Bentley, WA, Australia.

Faculty of Health Sciences, Curtin University, Bentley, WA, Australia.

出版信息

J Autism Dev Disord. 2018 May;48(5):1446-1457. doi: 10.1007/s10803-017-3405-9.

DOI:10.1007/s10803-017-3405-9
PMID:29168091
Abstract

Autism is associated with differences in sensory processing and motor coordination. Evidence from electroencephalography suggests individual perturbation evoked response (PER) components represent specific aspects of postural disturbance processing; P1 reflects the detection and N1 reflects the evaluation of postural instability. Despite the importance of these cortical responses to postural control, PERs to a perturbation in adults with autism spectrum disorder (ASD) have yet to be reported. The aim was to compare PERs to visual perturbation under varied postural stability conditions in adults with and without ASD. This study is the first to report that while the assessment of postural set is intact, adults with ASD use more cortical resources to integrate and interpret visual perturbations for postural control.

摘要

自闭症与感官处理和运动协调的差异有关。脑电图证据表明,个体扰动诱发反应 (PER) 成分代表姿势干扰处理的特定方面;P1 反映了检测,而 N1 反映了对姿势不稳定的评估。尽管这些皮质反应对姿势控制很重要,但自闭症谱系障碍 (ASD) 成人的 PER 尚未被报道。目的是比较 ASD 成人和非 ASD 成人在不同姿势稳定性条件下对视觉扰动的 PER。这项研究首次报告称,虽然姿势设定的评估是完整的,但 ASD 成人使用更多的皮质资源来整合和解释视觉扰动以进行姿势控制。

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本文引用的文献

1
Standing Postural Control in Individuals with Autism Spectrum Disorder: Systematic Review and Meta-analysis.自闭症谱系障碍个体的站立姿势控制:系统评价与荟萃分析
J Autism Dev Disord. 2017 Jul;47(7):2238-2253. doi: 10.1007/s10803-017-3144-y.
2
Postural and cortical responses following visual occlusion in standing and sitting tasks.站立和坐姿任务中视觉遮挡后的姿势及皮层反应。
Exp Brain Res. 2017 Jun;235(6):1875-1884. doi: 10.1007/s00221-017-4887-6. Epub 2017 Mar 16.
3
Electrocortical Sources Related to Whole-Body Surface Translations during a Single- and Dual-Task Paradigm.
自闭症谱系障碍青年的姿势控制的注意力和感觉综合。
Exp Brain Res. 2021 May;239(5):1417-1426. doi: 10.1007/s00221-021-06058-z. Epub 2021 Mar 6.
单任务和双任务范式下与全身表面平移相关的皮层电活动源
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Single-trial event-related potential extraction through one-unit ICA-with-reference.通过单通道参考独立成分分析进行单次试验事件相关电位提取。
J Neural Eng. 2016 Dec;13(6):066010. doi: 10.1088/1741-2560/13/6/066010. Epub 2016 Oct 14.
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Rapid and Objective Assessment of Neural Function in Autism Spectrum Disorder Using Transient Visual Evoked Potentials.使用瞬态视觉诱发电位对自闭症谱系障碍患者神经功能进行快速客观评估
PLoS One. 2016 Oct 7;11(10):e0164422. doi: 10.1371/journal.pone.0164422. eCollection 2016.
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Intrinsic Visual-Motor Synchrony Correlates With Social Deficits in Autism.内在视觉-运动同步与自闭症中的社交缺陷相关。
Biol Psychiatry. 2016 Apr 15;79(8):633-41. doi: 10.1016/j.biopsych.2015.08.029. Epub 2015 Sep 3.
7
Behavioral, perceptual, and neural alterations in sensory and multisensory function in autism spectrum disorder.自闭症谱系障碍中感觉及多感觉功能的行为、感知和神经改变。
Prog Neurobiol. 2015 Nov;134:140-60. doi: 10.1016/j.pneurobio.2015.09.007. Epub 2015 Oct 9.
8
Postural Control Deficits in Autism Spectrum Disorder: The Role of Sensory Integration.自闭症谱系障碍中的姿势控制缺陷:感觉统合的作用。
J Autism Dev Disord. 2016 Mar;46(3):853-61. doi: 10.1007/s10803-015-2621-4.
9
The role of the cerebral cortex in postural responses to externally induced perturbations.大脑皮层在对外部诱发扰动的姿势反应中的作用。
Neurosci Biobehav Rev. 2015 Oct;57:142-55. doi: 10.1016/j.neubiorev.2015.08.014. Epub 2015 Aug 29.
10
Differences in the use of vision and proprioception for postural control in autism spectrum disorder.自闭症谱系障碍中视觉和本体感觉在姿势控制运用上的差异。
Neuroscience. 2015 Oct 29;307:273-80. doi: 10.1016/j.neuroscience.2015.08.040. Epub 2015 Aug 24.