Rajadurai Vinita A, Tan Jason, Salfinger Stuart G, Cohen Paul A
Bendat Family Comprehensive Cancer Centre, St John of God Subiaco Hospital, Subiaco, Perth, Australia.
Division of Women's and Infants' Health, School of Medicine, University of Western Australia, Crawley, Western Australia, Australia.
Aust N Z J Obstet Gynaecol. 2018 Aug;58(4):443-448. doi: 10.1111/ajo.12749. Epub 2017 Nov 23.
Robotic-assisted laparoscopic hysterectomy (RALH) is associated with improved outcomes compared to open surgery in patients with endometrial cancer but data are conflicting when comparing RALH to conventional total laparoscopic hysterectomy (TLH). In October 2014, a RALH program was established in Perth, Western Australia.
To compare outcomes in patients undergoing RALH with a matched cohort undergoing TLH.
A retrospective matched cohort study compared outcomes in 45 patients who underwent RALH with 45 controls who were patients treated with TLH.
Mean operating time was longer in the RALH group compared to controls (75.42 min vs 53.18 min, mean difference 22.24 min, P < 0.001, 95% Cl, 11.07-33.42). No differences were observed in mean pain scores (RALH 1.47 vs TLH 1.84 P = 0.31), mean parenteral and oral opioid use (RALH 14.3 mg and 42.4 mg vs TLH 17.5 mg and 52.57 mg, P = 0.42 and 0.42, respectively), and mean length of stay (RALH 1.51 vs TLH 1.67 days, P = 0.49). Two patients in the RALH group and one patient in the TLH group sustained iatrogenic bladder injuries (P = 0.62).
The establishment of the RALH program at our institution appeared to be associated with equivalent morbidity, post-operative pain, opioid use and length of stay compared to conventional laparoscopy. A surgical learning curve for RALH was observed. Well-designed prospective studies are needed to further evaluate short- and long-term patient function, morbidity, quality of life and oncologic outcomes.
与开放性手术相比,机器人辅助腹腔镜子宫切除术(RALH)可改善子宫内膜癌患者的治疗效果,但将RALH与传统全腹腔镜子宫切除术(TLH)进行比较时,数据存在冲突。2014年10月,在西澳大利亚州的珀斯建立了一个RALH项目。
比较接受RALH的患者与接受TLH的匹配队列患者的治疗效果。
一项回顾性匹配队列研究比较了45例行RALH的患者与45例接受TLH治疗的对照患者的治疗效果。
与对照组相比,RALH组的平均手术时间更长(75.42分钟对53.18分钟,平均差异22.24分钟,P<0.001,95%CI,11.07 - 33.42)。平均疼痛评分(RALH为1.47对TLH为1.84,P = 0.31)、平均胃肠外和口服阿片类药物使用量(RALH为14.3毫克和42.4毫克对TLH为17.5毫克和52.57毫克,P分别为0.42和0.42)以及平均住院时间(RALH为1.51天对TLH为1.67天,P = 0.49)均未观察到差异。RALH组有2例患者和TLH组有1例患者发生医源性膀胱损伤(P = 0.62)。
与传统腹腔镜检查相比,在我们机构建立RALH项目似乎与同等的发病率、术后疼痛、阿片类药物使用和住院时间相关。观察到RALH存在手术学习曲线。需要精心设计的前瞻性研究来进一步评估患者的短期和长期功能、发病率、生活质量和肿瘤学结局。