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机器人辅助与传统腹腔镜子宫切除术治疗子宫内膜癌

Robotic-assisted versus conventional laparoscopic hysterectomy for endometrial cancer.

作者信息

Johansson Cherynne Yuin Mun, Chan Felix Kwok Hee

机构信息

Liverpool Hospital, Liverpool, New South Wales, Australia.

Westmead Private Hospital, Westmead, New South Wales, Australia.

出版信息

Eur J Obstet Gynecol Reprod Biol X. 2020 Sep 6;8:100116. doi: 10.1016/j.eurox.2020.100116. eCollection 2020 Oct.

Abstract

OBJECTIVE

The safety and efficacy of robotic-assisted laparoscopic hysterectomy (RALH) compared with conventional total laparoscopic hysterectomy (TLH) for surgical staging of endometrial cancer has not been clearly established. With the commencement of a robotic program at our institution, our objective was to evaluate and compare the surgical outcomes of RALH with TLH for endometrial cancer.

METHODS

A retrospective cohort study was performed on 39 patients who underwent RALH and 41 patients who underwent TLH for endometrial cancer at a tertiary care academic institution.

RESULTS

In the setting of endometrial cancer RALH is significantly longer to perform than TLH (mean operating time 133 min vs 107 min, = 0.0001). There is higher estimated blood loss in TLH cases than RALH cases (78 mL vs 22 mL, = 0.015). Women who underwent RALH had a shorter length of stay (1.3 days vs 1.8 days, = 0.006) than TLH patients, and six cases (15 %) of the RALH group were discharged on the same day of surgery. There were no differences between the RALH and TLH groups in intraoperative or postoperative complications and there were no conversions to laparotomy.

CONCLUSION

RALH is safe and feasible for the treatment of endometrial cancer, with low morbidity, less blood loss and shorter length of stay than TLH. RALH is associated with longer mean operating times than TLH and this may improve with enlisting a consistent experienced team. Prospective randomised studies which include analysis of quality of life measures and long-term outcomes are required to further establish the role of RALH in the surgical staging of endometrial cancer.

摘要

目的

与传统全腹腔镜子宫切除术(TLH)相比,机器人辅助腹腔镜子宫切除术(RALH)用于子宫内膜癌手术分期的安全性和有效性尚未明确确立。随着我们机构开展机器人手术项目,我们的目的是评估并比较RALH与TLH用于子宫内膜癌的手术结果。

方法

在一家三级医疗学术机构,对39例行RALH的子宫内膜癌患者和41例行TLH的子宫内膜癌患者进行了一项回顾性队列研究。

结果

在子宫内膜癌的情况下,RALH的手术时间明显长于TLH(平均手术时间133分钟对107分钟,P = 0.0001)。TLH病例的估计失血量高于RALH病例(78毫升对22毫升,P = 0.015)。接受RALH的女性住院时间比TLH患者短(1.3天对1.8天,P = 0.006),RALH组有6例(15%)在手术当天出院。RALH组和TLH组在术中或术后并发症方面无差异,也没有转为开腹手术的情况。

结论

RALH治疗子宫内膜癌安全可行,发病率低,失血量少,住院时间比TLH短。RALH的平均手术时间比TLH长,组建一支经验丰富的固定团队可能会改善这一情况。需要进行前瞻性随机研究,包括对生活质量指标和长期结果的分析,以进一步确立RALH在子宫内膜癌手术分期中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90c5/7508988/457a455befd3/gr1.jpg

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