Wens R, Goffin Y, Pepys M B, Kutnowski M, Van Beers D, Decoodt P, Verbanck M
Department of Internal Medicine, Brugmann University Hospital, Brussels, Belgium.
Arch Intern Med. 1989 Feb;149(2):453-4.
A 76-year-old woman presenting with generalized amyloidosis of the AA-type protein was found to have a left atrial myxoma. Retrospective estimation of the concentration of SAA protein, a serum precursor of AA amyloid, before and after surgical removal of the myxoma, showed that the SAA protein had disappeared after the operation. A common manifestation of myxoma is the development of a severe inflammatory syndrome that sometimes simulates rheumatic fever or bacterial endocarditis. However, to our knowledge, it has never been described in association with amyloidosis. We suggest that atrial myxoma should be added the list of neoplastic and inflammatory diseases predisposing to AA amyloidosis.
一名76岁患有AA型蛋白全身性淀粉样变性的女性被发现患有左心房黏液瘤。对黏液瘤手术切除前后血清淀粉样蛋白A（SAA）蛋白（AA淀粉样蛋白的血清前体）浓度进行回顾性评估，结果显示术后SAA蛋白消失。黏液瘤的常见表现是出现严重的炎症综合征，有时类似风湿热或细菌性心内膜炎。然而，据我们所知，此前从未有过与淀粉样变性相关的描述。我们建议应将心房黏液瘤列入易引发AA淀粉样变性的肿瘤性和炎症性疾病名单中。
