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退行性颈椎脊髓病手术治疗后预后的重要预测因素:文献系统评价

Significant Predictors of Outcome Following Surgery for the Treatment of Degenerative Cervical Myelopathy: A Systematic Review of the Literature.

作者信息

Tetreault Lindsay, Palubiski Lisa M, Kryshtalskyj Michael, Idler Randy K, Martin Allan R, Ganau Mario, Wilson Jefferson R, Kotter Mark, Fehlings Michael G

机构信息

Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada; Graduate Entry Medicine, University College Cork, Cork, Ireland.

Graduate Entry Medicine, University College Cork, Cork, Ireland.

出版信息

Neurosurg Clin N Am. 2018 Jan;29(1):115-127.e35. doi: 10.1016/j.nec.2017.09.020.


DOI:10.1016/j.nec.2017.09.020
PMID:29173423
Abstract

This systematic review aims to summarize important clinical predictors of outcomes in patients undergoing surgery for the treatment of degenerative cervical myelopathy. Based on the results of this article, patients with a longer duration of symptoms and more severe myelopathy are likely to have worse surgical outcomes. With respect to age, several studies have indicated that elderly patients are less likely to translate neurologic recovery into functional improvements. However, many other studies have failed to identify a significant association between age and outcomes. Finally, smoking status and presence of comorbidities may be important predictors of outcomes.

摘要

本系统评价旨在总结接受手术治疗退行性颈椎脊髓病患者预后的重要临床预测因素。根据本文结果,症状持续时间较长且脊髓病较严重的患者手术预后可能较差。关于年龄,多项研究表明老年患者神经功能恢复转化为功能改善的可能性较小。然而,许多其他研究未能确定年龄与预后之间存在显著关联。最后,吸烟状况和合并症的存在可能是预后的重要预测因素。

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引用本文的文献

[1]
AO Spine Clinical Practice Recommendations for Diagnosis and Management of Degenerative Cervical Myelopathy: Evidence Based Decision Making - A Review of Cutting Edge Recent Literature Related to Degenerative Cervical Myelopathy.

Global Spine J. 2025-4-21

[2]
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[3]
Predicting Neck Dysfunction After Open-Door Cervical Laminoplasty - A Prospective Cohort Patient-Reported Outcome Measurement Study.

Neurospine. 2024-12

[4]
Does snake-eye appearance affect the clinical outcome of ACDF in treating cervical myelopathy.

Eur Spine J. 2025-1

[5]
Degenerative Cervical Myelopathy Awareness in Primary Care: UK National Cross-Sectional Survey of General Practitioners.

JMIR Form Res. 2024-8-19

[6]
Peripheral blood RNA biomarkers can predict lesion severity in degenerative cervical myelopathy.

Neural Regen Res. 2025-6-1

[7]
Preliminarily exploring the intraoperative ultrasonography characteristics of patients with degenerative cervical myelopathy.

BMC Musculoskelet Disord. 2024-7-12

[8]
Assessment of Surgical Outcomes in Patients with Degenerative Cervical Myelopathy Using the 25-Question Geriatric Locomotive Function Scale: A Longitudinal Observational Study.

Spine Surg Relat Res. 2023-12-27

[9]
Mapping the Degenerative Cervical Myelopathy Research Landscape: Topic Modeling of the Literature.

Global Spine J. 2025-4

[10]
Hidden blood loss in unilateral open-door cervical laminoplasty for multilevel cervical spondylotic myelopathy.

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