Chng H H, Shaw D, Klesius P, Saxon A
Department of Medicine, UCLA School of Medicine, Los Angeles, CA 90024.
Clin Immunol Immunopathol. 1989 Mar;50(3):402-6. doi: 10.1016/0090-1229(89)90148-7.
A 31-year-old man with dysgammaglobulinemia Type I (deficient IgG, IgA, and elevated IgM) and persistent cryptosporidiosis was treated over a 13-week period with oral bovine transfer factor from calves immunized with cryptosporidia. Spiramycin was added toward the end of the treatment period. This patient failed to show clinical response although there was a decrease in the stool oocyst count from the value just prior to therapy. Bovine transfer factor alone and in combination with spiramycin failed to eradicate the infection in this man with well-documented stable cryptosporidiosis.
一名患有I型免疫球蛋白异常血症（IgG、IgA缺乏，IgM升高）且持续患隐孢子虫病的31岁男性，在13周的时间里接受了用隐孢子虫免疫的小牛的口服牛转移因子治疗。在治疗期快结束时加用了螺旋霉素。尽管治疗后粪便中卵囊计数较治疗前有所下降，但该患者未显示出临床反应。单独使用牛转移因子以及与螺旋霉素联合使用均未能根除该患有已确诊的稳定型隐孢子虫病男性体内的感染。
