Jacyna M R, Parkin J, Goldin R, Baron J H
Department of Gastroenterology, Immunology, St. Marys Hospital and Medical School, London.
Gut. 1990 Jun;31(6):714-6. doi: 10.1136/gut.31.6.714.
Chronic cryptosporidial infection in man usually occurs in those who are immunocompromised. We report a patient with a one year history of bowel symptoms resulting from persistent cryptosporidial infection of the colon. Investigations showed underlying selective IgA and saccharomyces opsonin deficiencies but no evidence of cell mediated immune dysfunction. Both selective immunoglobulin A and opsonin deficiencies are relatively common in the general population and may be a cause of susceptibility to persistent cryptosporidial infection.
人类慢性隐孢子虫感染通常发生在免疫功能低下者身上。我们报告了一名患者，其因结肠持续隐孢子虫感染而有一年的肠道症状病史。检查显示存在潜在的选择性IgA和酵母调理素缺乏，但无细胞介导免疫功能障碍的证据。选择性免疫球蛋白A和调理素缺乏在普通人群中相对常见，可能是易发生持续性隐孢子虫感染的一个原因。
