MRCZ - 一种用于冷冻透射电子显微镜数据的文件格式，具有快速压缩功能。
MRCZ - A file format for cryo-TEM data with fast compression.
机构信息
Center for Cellular Imaging and NanoAnalytics (C-CINA), University of Basel, Basel, Switzerland.
Center for Cellular Imaging and NanoAnalytics (C-CINA), University of Basel, Basel, Switzerland.
出版信息
J Struct Biol. 2018 Mar;201(3):252-257. doi: 10.1016/j.jsb.2017.11.012. Epub 2017 Nov 23.
The introduction of fast CMOS detectors is moving the field of transmission electron microscopy into the computer science field of big data. Automated data pipelines control the instrument and initial processing steps which imposes more onerous data transfer and archiving requirements. Here we conduct a technical demonstration whereby storage and read/write times are improved 10× at a dose rate of 1 e/pix/frame for data from a Gatan K2 direct-detection device by combination of integer decimation and lossless compression. The example project is hosted at github.com/em-MRCZ and released under the BSD license.
快速 CMOS 探测器的引入正在将透射电子显微镜领域推向计算机科学的大数据领域。自动化的数据管道控制仪器和初始处理步骤，这对数据传输和归档提出了更高的要求。在这里，我们进行了一项技术演示，通过组合整数抽取和无损压缩，将 Gatan K2 直接检测设备的数据的存储和读写时间在 1 e/pix/frame 的剂量率下提高了 10 倍。该示例项目托管在 github.com/em-MRCZ 上，并根据 BSD 许可证发布。
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