Suppr超能文献

衰老心智中的体现。

Embodiment in the aging mind.

机构信息

German Center for Neurodegenerative Diseases (DZNE), Aging and Cognition Research Group, Leipziger Straße 44, 39120 Magdeburg, Germany; Center for Behavioral Brain Sciences Magdeburg, 39106 Magdeburg, Germany; Max Planck Institute for Human Cognitive and Brain Sciences, Department of Neurology, 04109 Leipzig, Germany.

German Center for Neurodegenerative Diseases (DZNE), Aging and Cognition Research Group, Leipziger Straße 44, 39120 Magdeburg, Germany.

出版信息

Neurosci Biobehav Rev. 2018 Mar;86:207-225. doi: 10.1016/j.neubiorev.2017.11.016. Epub 2017 Nov 22.

Abstract

Bodily awareness is a central component of human sensation, action, and cognition. The human body is subject to profound changes over the adult lifespan. We live in an aging society: the mean age of people living in industrialized countries is currently over 40 years, and further increases are expected. Nevertheless, there is a lack of comprehensive knowledge that links changes in embodiment that occur with age to neuronal mechanisms and associated sensorimotor and cognitive deficits in older adults. Here, we synthesize existing evidence and introduce the NFL Framework of Embodied Aging, which links basic neuronal (N) mechanisms of age-related sensorimotor decline to changes in functional (F) bodily impairments, including deficits in higher-level cognitive functions, and impairments in daily life (L). We argue that cognitive and daily life impairments associated with old age are often due to deficits in embodiment, which can partly be linked to neuronal degradation at the sensorimotor level. The framework may encourage the development of novel approaches to improve autonomous living for older adults.

摘要

身体意识是人类感觉、行动和认知的核心组成部分。人体在成年后会发生深刻的变化。我们生活在一个老龄化的社会中:工业化国家的人口平均年龄目前超过 40 岁,预计还会进一步上升。然而,人们缺乏将与年龄相关的身体变化与神经元机制以及与老年人相关的感觉运动和认知缺陷联系起来的综合知识。在这里,我们综合了现有证据,并介绍了体现老龄化的 NFL 框架,该框架将与年龄相关的感觉运动下降的基本神经元(N)机制与功能(F)身体损伤的变化联系起来,包括高级认知功能的缺陷和日常生活中的损伤(L)。我们认为,与老年相关的认知和日常生活损伤通常是由于身体表现不佳所致,而这种表现不佳在一定程度上可以与感觉运动水平的神经元退化联系起来。该框架可能会鼓励开发新方法来提高老年人的自主生活能力。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验