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蓝白面纱作为2例非裔美国盘状红斑狼疮患者的新型皮肤镜特征

Blue-White Veil as Novel Dermatoscopic Feature in Discoid Lupus Erythematosus in 2 African-American Patients.

作者信息

Cervantes Jessica, Hafeez Farhaan, Miteva Mariya

机构信息

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

出版信息

Skin Appendage Disord. 2017 Oct;3(4):211-214. doi: 10.1159/000477354. Epub 2017 Jun 10.

Abstract

Dermoscopic features of discoid lupus erythematosus (DLE) depend on the stage of the lesions: active lesions include yellow-brown dots and red dots, whereas longstanding inactive lesions show absence of follicular openings, cicatricial milky red or white patches, structureless white and brown areas, and thick arborizing vessels. Loss of pinpoint white dots, blue-gray dots in a speckled pattern, and a peripheral pigmented network have been described on dermoscopy of DLE in dark skin. We report a blue-white veil as a novel dermoscopic feature in 2 cases of biopsy-proven DLE in African-American patients. Dry trichoscopy revealed a central white area surrounded by irregular patchy areas of confluent blue and brown pigment and an overlying white "ground-glass" hue. This corresponds on pathology to the hyperkeratosis overlying interface changes at the dermal-epidermal junction, with pigment incontinence and melanophages in the papillary dermis.

摘要

盘状红斑狼疮(DLE)的皮肤镜特征取决于皮损的阶段:活动期皮损包括黄棕色点和红点,而长期不活动的皮损则表现为毛囊开口缺失、瘢痕性乳红色或白色斑块、无结构的白色和棕色区域以及粗大的树枝状血管。在深色皮肤的DLE皮肤镜检查中,已描述有针尖状白点消失、呈斑点状的蓝灰色点以及周边色素沉着网络。我们报告了2例经活检证实的非裔美国患者DLE中出现的一种新型皮肤镜特征——蓝白色面纱。干性毛发镜检查显示中央白色区域被不规则的融合性蓝色和棕色色素斑块区域包围,并有一层白色的“毛玻璃”色调覆盖。这在病理上对应于真皮-表皮交界处界面改变上方的角化过度,伴有乳头真皮内的色素失禁和噬黑素细胞。

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