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利用带血管蒂髂嵴皮瓣将计算机辅助设计与手术规划转化为成功的下颌骨重建

Translating Computer-Aided Design and Surgical Planning Into Successful Mandibular Reconstruction Using a Vascularized Iliac-Crest Flap.

作者信息

Zheng Lei, Lv Xiaoming, Zhang Jie, Liu Shuming, Zhang Jianguo, Zhang Yi

机构信息

Associate Professor, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.

Resident, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.

出版信息

J Oral Maxillofac Surg. 2018 Apr;76(4):886-893. doi: 10.1016/j.joms.2017.10.026. Epub 2017 Nov 3.

Abstract

PURPOSE

This study evaluated the computer-aided approach to the reconstruction of mandibular defects using a vascularized iliac-crest flap.

MATERIALS AND METHODS

From December 2015 to October 2016, 14 patients (8 men and 6 women) 18 to 64 years old (median age, 29 yr) were treated at the Peking University School and Stomatology Hospital (Beijing, China). Biopsy specimens from all patients were subjected to histologic examination before segmental mandibulectomy. Computer-based surgical techniques, including virtual surgical planning, computer-aided design and manufacturing, rapid prototyping, and intraoperative navigation, were used to restore the anatomic continuity and configuration of the mandible using a vascularized iliac-crest flap. Two transverse dimensions and 1 anteroposterior (A-P) dimension were evaluated based on the virtual plan and postoperative computed tomogram. Lines from condylar head to condylar head and from gonial angle to gonial angle were defined as the transverse dimensions. A perpendicular line drawn from the mandibular midline to the center point on the condylar head to condylar head measurement was defined as the A-P dimension. Complications were evaluated during follow-up.

RESULTS

The flap success rate was 92.9% (13 of 14), with 1 flap failure. After the operation, there were no other serious complications in 13 of the 14 patients, who exhibited a good mandibular configuration with good occlusion. Furthermore, the height of bone graft was sufficient for implants. Healing of the recipient and donor sites with no serious complication was uneventful. The average surgical errors in the A-P dimension and transverse dimensions were 1.8 ± 1.0 mm (range, 0.2 to 3.7 mm), 2.2 ± 1.1 mm (range, 0.9 to 5.0 mm), and 2.6 ± 1.6 mm (range, 0.3 to 7.2 mm), respectively.

CONCLUSIONS

The use of these digital techniques was found to be a viable option for reconstruction of mandibular defects, but the results should be interpreted cautiously because of the small number of patients and the relatively short follow-up.

摘要

目的

本研究评估了使用带血管蒂髂嵴瓣进行下颌骨缺损重建的计算机辅助方法。

材料与方法

2015年12月至2016年10月,北京大学口腔医学院(中国北京)对14例患者(8例男性和6例女性)进行了治疗,患者年龄在18至64岁之间(中位年龄29岁)。所有患者的活检标本在节段性下颌骨切除术前均进行了组织学检查。采用基于计算机的手术技术,包括虚拟手术规划、计算机辅助设计与制造、快速成型和术中导航,使用带血管蒂髂嵴瓣恢复下颌骨的解剖连续性和形态。基于虚拟计划和术后计算机断层扫描评估两个横向维度和一个前后(A-P)维度。从髁突头到髁突头以及从下颌角到下颌角的连线定义为横向维度。从下颌中线向下画一条垂直线至髁突头到髁突头测量的中心点,该垂直线定义为A-P维度。在随访期间评估并发症。

结果

皮瓣成功率为92.9%(14例中的13例),1例皮瓣失败。术后,14例患者中的13例无其他严重并发症,下颌形态良好,咬合良好。此外,骨移植高度足以植入种植体。受区和供区愈合良好,无严重并发症。A-P维度和横向维度的平均手术误差分别为1.8±1.0mm(范围0.2至3.7mm)、2.2±1.1mm(范围0.9至5.0mm)和2.6±1.6mm(范围0.3至7.2mm)。

结论

发现使用这些数字技术是重建下颌骨缺损的一种可行选择,但由于患者数量少且随访时间相对较短,结果应谨慎解读。

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