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邻里社会经济地位与新诊断出背痛时阿片类药物的使用情况

Neighborhood Socioeconomic Status and Receipt of Opioid Medication for New Back Pain Diagnosis.

作者信息

Gebauer Sarah, Salas Joanne, Scherrer Jeffrey F

机构信息

From the Department of Family and Community Medicine, Saint Louis University School of Medicine, St. Louis, MO.

出版信息

J Am Board Fam Med. 2017 Nov-Dec;30(6):775-783. doi: 10.3122/jabfm.2017.06.170061.

Abstract

BACKGROUND

Although treatment for new back pain is heavily guideline driven, deviations occur frequently. Neighborhood socioeconomic status (nSES) may contribute to these deviations.

OBJECTIVE

Determine whether nSES is associated with type of treatment provided for patients seeking treatment for new back pain in primary care clinics.

METHODS

This retrospective cohort was conducted in academic internal and family medicine practices. Data were examined from the Primary Care Patient Data Registry. Eligibility criteria included age ≥18 years, free of HIV and cancer, and presenting to primary care with a new diagnosis of back pain, resulting in1646 patients included. Patients' nSES was determined using ZIP code and calculating a validated index of 7 census-tract variables. Multinomial logistic regression was used to measure the association between nSES and 3 treatment outcomes compared with no pharmacologic management. Outcomes included opioid prescription, nonsteroidal anti-inflammatory (NSAID)/muscle relaxant prescription, or combined opioid/nonopioid treatment within 90 days of initial presentation. Covariates included age, sex, race, high clinic utilization (HCU), depression, anxiety, substance use, obesity, comorbidities, smoking, number of pain conditions, and physical therapy (PT) referral.

RESULTS

The cohort was 67.9% female with an average age of 55.72 years (Standard Error [SE] = 0.387). Compared with no pharmacologic treatment, individuals in the low nSES group had 63% higher odds of receiving an opioid only compared with the high nSES group (odds ratio [OR], 1.63; 95% confidence interval [CI], 1.01 to 2.62). There was no significant association between nSES and odds of nonopioid or combined treatment compared with no pharmacotherapy (OR, 1.17; 95% CI, 0.97 to 1.50), (OR, 1.09; 95% CI, 0.67 to 1.78), respectively. Covariates associated with increased odds of opioid only included HCU, ever smoker, and increasing comorbidity index. PT referral was associated with NSAID/muscle relaxant only, and increasing age and comorbidity index were inversely associated with odds of NSAID/muscle relaxant only. Finally, covariates associated with increased odds of receiving both therapies included high clinic utilizusation, ever smoking, and PT referral.

CONCLUSIONS

These data characterize a possible association between low nSES and increased risk of receiving an opioid only when being treated for new back pain. This may be evidence that patients of low nSES are at increased risk of receiving guideline-noncompliant treatment for new back pain.

摘要

背景

尽管新发性背痛的治疗在很大程度上遵循指南,但偏差仍频繁出现。社区社会经济地位(nSES)可能是导致这些偏差的原因之一。

目的

确定nSES是否与基层医疗诊所中因新发性背痛寻求治疗的患者所接受的治疗类型相关。

方法

本回顾性队列研究在学术性内科和家庭医学实践中进行。数据来自基层医疗患者数据登记处。纳入标准包括年龄≥18岁、无艾滋病毒和癌症,且因新诊断的背痛就诊于基层医疗,共纳入1646例患者。使用邮政编码并计算7个普查区变量的有效指数来确定患者的nSES。采用多项逻辑回归分析来衡量nSES与3种治疗结果之间的关联,并与非药物治疗进行比较。结果包括在初次就诊后90天内开具阿片类药物处方、非甾体抗炎药(NSAID)/肌肉松弛剂处方或联合使用阿片类/非阿片类药物治疗。协变量包括年龄、性别、种族、高诊所利用率(HCU)、抑郁、焦虑、物质使用、肥胖、合并症、吸烟、疼痛状况数量和物理治疗(PT)转诊。

结果

该队列中女性占67.9%,平均年龄为55.72岁(标准误[SE]=0.387)。与非药物治疗相比,低nSES组患者仅接受阿片类药物治疗的几率比高nSES组高63%(比值比[OR],1.63;95%置信区间[CI],1.01至2.62)。与非药物治疗相比,nSES与接受非阿片类药物或联合治疗的几率之间无显著关联(OR,1.17;95%CI,0.97至1.50),(OR,1.09;95%CI,0.67至1.78)。仅与阿片类药物使用几率增加相关的协变量包括高诊所利用率、曾经吸烟者和合并症指数增加。PT转诊仅与NSAID/肌肉松弛剂使用几率相关,年龄增加和合并症指数增加与仅使用NSAID/肌肉松弛剂的几率呈负相关。最后,与接受两种治疗几率增加相关的协变量包括高诊所利用率、曾经吸烟者和PT转诊。

结论

这些数据表明,低nSES与新发性背痛治疗时仅接受阿片类药物治疗的风险增加之间可能存在关联。这可能证明,低nSES患者在接受新发性背痛的治疗时,接受不符合指南治疗的风险增加。

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