Kazis Lewis E, Ameli Omid, Rothendler James, Garrity Brigid, Cabral Howard, McDonough Christine, Carey Kathleen, Stein Michael, Sanghavi Darshak, Elton David, Fritz Julie, Saper Robert
Department of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts, USA
Department of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts, USA.
BMJ Open. 2019 Sep 20;9(9):e028633. doi: 10.1136/bmjopen-2018-028633.
This study examined the association of initial provider treatment with early and long-term opioid use in a national sample of patients with new-onset low back pain (LBP).
A retrospective cohort study of patients with new-onset LBP from 2008 to 2013.
The study evaluated outpatient and inpatient claims from patient visits, pharmacy claims and inpatient and outpatient procedures with initial providers seen for new-onset LBP.
216 504 individuals aged 18 years or older across the USA who were diagnosed with new-onset LBP and were opioid-naïve were included. Participants had commercial or Medicare Advantage insurance.
The primary independent variable is type of initial healthcare provider including physicians and conservative therapists (physical therapists, chiropractors, acupuncturists).
Short-term opioid use (within 30 days of the index visit) following new LBP visit and long-term opioid use (starting within 60 days of the index date and either 120 or more days' supply of opioids over 12 months, or 90 days or more supply of opioids and 10 or more opioid prescriptions over 12 months).
Short-term use of opioids was 22%. Patients who received initial treatment from chiropractors or physical therapists had decreased odds of short-term and long-term opioid use compared with those who received initial treatment from primary care physicians (PCPs) (adjusted OR (AOR) (95% CI) 0.10 (0.09 to 0.10) and 0.15 (0.13 to 0.17), respectively). Compared with PCP visits, initial chiropractic and physical therapy also were associated with decreased odds of long-term opioid use in a propensity score matched sample (AOR (95% CI) 0.21 (0.16 to 0.27) and 0.29 (0.12 to 0.69), respectively).
Initial visits to chiropractors or physical therapists is associated with substantially decreased early and long-term use of opioids. Incentivising use of conservative therapists may be a strategy to reduce risks of early and long-term opioid use.
本研究在全国新发腰痛(LBP)患者样本中,考察了初始治疗提供者与早期及长期阿片类药物使用之间的关联。
对2008年至2013年新发LBP患者进行的一项回顾性队列研究。
该研究评估了患者就诊的门诊和住院理赔、药房理赔以及因新发LBP首次就诊的提供者所进行的住院和门诊治疗。
纳入了美国216504名18岁及以上被诊断为新发LBP且未使用过阿片类药物的个体。参与者拥有商业保险或医疗保险优势计划。
主要自变量是初始医疗保健提供者的类型,包括医生和保守治疗师(物理治疗师、脊椎按摩师、针灸师)。
新发LBP就诊后短期阿片类药物使用(在索引就诊后30天内)以及长期阿片类药物使用(在索引日期后60天内开始,且在12个月内阿片类药物供应达120天及以上,或在12个月内阿片类药物供应达90天及以上且有10张及以上阿片类药物处方)。
阿片类药物短期使用率为22%。与接受初级保健医生(PCP)初始治疗的患者相比,接受脊椎按摩师或物理治疗师初始治疗的患者短期和长期使用阿片类药物的几率降低(调整后比值比(AOR)(95%置信区间)分别为0.10(0.09至0.10)和0.15(0.13至0.17))。在倾向得分匹配样本中,与PCP就诊相比,初始脊椎按摩治疗和物理治疗也与长期阿片类药物使用几率降低相关(AOR(95%置信区间)分别为0.21(0.16至0.27)和0.29(0.12至0.69))。
首次就诊于脊椎按摩师或物理治疗师与早期及长期阿片类药物使用显著减少相关。鼓励使用保守治疗师可能是降低早期及长期阿片类药物使用风险的一种策略。