Li Shu-Lin, Han Jian-De
Department of Dermatology, Shenzhen Zhongshan Urology Hospital, Shenzhen, Guangdong 518045, P.R. China.
Department of Dermatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China.
Mol Clin Oncol. 2017 Nov;7(5):874-876. doi: 10.3892/mco.2017.1423. Epub 2017 Sep 19.
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare chronic inflammatory disorder of unknown etiology that most commonly presents as painless lymphadenopathy or subcutaneous masses in the head and neck region. The pathogenesis of the disease is not yet clear. The differential diagnosis is determined using characteristic histological features, such as significant vascular proliferation, lymphocytes and eosinophil inflammation in the dermis. Here is presented the case of a patient with a solitary nodule of ALHE masquerading as pyogenic granuloma (PG). A 47 year-old male patient was admitted with an isolated lump on the right side of the back, which had been present for ~6 months; the nodule appeared to have characteristics of PG and was ~1.8×1.0 cm in diameter. To the best of our knowledge, this is the first case report regarding ALHE arising in the back. The present report discusses the manifestation, histopathological features and treatment of the case.
伴有嗜酸性粒细胞增多的血管淋巴样增生(ALHE)是一种病因不明的罕见慢性炎症性疾病,最常见的表现为头颈部无痛性淋巴结病或皮下肿块。该病的发病机制尚不清楚。通过特征性组织学特征进行鉴别诊断,如显著的血管增生、真皮内淋巴细胞和嗜酸性粒细胞炎症。本文介绍了一例伪装成化脓性肉芽肿(PG)的孤立性ALHE结节患者的病例。一名47岁男性患者因背部右侧孤立性肿块入院,该肿块已存在约6个月;该结节似乎具有PG的特征,直径约为1.8×1.0厘米。据我们所知,这是第一例关于背部发生ALHE的病例报告。本报告讨论了该病例的表现、组织病理学特征和治疗方法。