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对比超声下复合指数与全球滑膜炎评分在检测缓解中的作用。

Comparison of composite indices with global synovitis score on ultrasound for detecting remission.

机构信息

Department of Internal Medicine, Istanbul Medeniyet University School of Medicine, Istanbul, Turkey.

Division of Rheumatology, Istanbul Medeniyet University, Istanbul, Turkey.

出版信息

Clin Rheumatol. 2018 Apr;37(4):1111-1114. doi: 10.1007/s10067-017-3925-x. Epub 2017 Nov 27.

Abstract

We aimed to compare composite indices with Ultrasound Global Synovitis Score (GLOESS) for remission in rheumatoid arthritis (RA). RA patients in remission according to the clinician were investigated with Disease Activity Score28 (DAS28), Clinical Disease Activity Index (CDAI), Simplified Disease Activity Index (SDAI), and RAPID-3 (Routine Assessment of Patient Index Data 3). Ultrasonography was performed using the GLOESS scores. Patients in CDAI-remission had lower GLOESS (median (IQR), 5(3-9.75) vs 7(4-11.75), p = 0.048) with a similar trend in SDAI (5(3-9.25) vs 7(4-11.25), p = 0.064). This was not observed with DAS28-CRP and RAPID3. Our results show that CDAI is superior to other indices to assess remission in RA.

摘要

我们旨在比较复合指数与超声整体滑膜炎评分(GLOESS)在类风湿关节炎(RA)缓解中的作用。根据临床医生的评估,对处于缓解期的 RA 患者进行了疾病活动评分 28(DAS28)、临床疾病活动指数(CDAI)、简化疾病活动指数(SDAI)和 RAPID-3(患者常规评估数据 3)的检测。使用 GLOESS 评分进行超声检查。在 CDAI 缓解的患者中,GLOESS 评分较低(中位数(IQR),5(3-9.75)vs. 7(4-11.75),p=0.048),SDAI 也存在相似的趋势(5(3-9.25)vs. 7(4-11.25),p=0.064)。但 DAS28-CRP 和 RAPID3 则没有观察到这种情况。我们的研究结果表明,CDAI 在评估 RA 缓解方面优于其他指数。

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