Scanlan Adam B, Nguyen Alex V, Ilina Anna, Lasso Andras, Cripe Linnea, Jegatheeswaran Anusha, Silvestro Elizabeth, McGowan Francis X, Mascio Christopher E, Fuller Stephanie, Spray Thomas L, Cohen Meryl S, Fichtinger Gabor, Jolley Matthew A
Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Laboratory for Percutaneous Surgery, Queen's University, Kingston, ON, USA.
Pediatr Cardiol. 2018 Mar;39(3):538-547. doi: 10.1007/s00246-017-1785-4. Epub 2017 Nov 27.
Mastering the technical skills required to perform pediatric cardiac valve surgery is challenging in part due to limited opportunity for practice. Transformation of 3D echocardiographic (echo) images of congenitally abnormal heart valves to realistic physical models could allow patient-specific simulation of surgical valve repair. We compared materials, processes, and costs for 3D printing and molding of patient-specific models for visualization and surgical simulation of congenitally abnormal heart valves. Pediatric atrioventricular valves (mitral, tricuspid, and common atrioventricular valve) were modeled from transthoracic 3D echo images using semi-automated methods implemented as custom modules in 3D Slicer. Valve models were then both 3D printed in soft materials and molded in silicone using 3D printed "negative" molds. Using pre-defined assessment criteria, valve models were evaluated by congenital cardiac surgeons to determine suitability for simulation. Surgeon assessment indicated that the molded valves had superior material properties for the purposes of simulation compared to directly printed valves (p < 0.01). Patient-specific, 3D echo-derived molded valves are a step toward realistic simulation of complex valve repairs but require more time and labor to create than directly printed models. Patient-specific simulation of valve repair in children using such models may be useful for surgical training and simulation of complex congenital cases.
掌握小儿心脏瓣膜手术所需的技术技能具有挑战性,部分原因是实践机会有限。将先天性异常心脏瓣膜的三维超声心动图(超声)图像转化为逼真的物理模型,可以实现针对特定患者的手术瓣膜修复模拟。我们比较了用于先天性异常心脏瓣膜可视化和手术模拟的特定患者模型的3D打印和成型的材料、工艺及成本。使用在3D Slicer中作为自定义模块实现的半自动方法,从经胸三维超声图像中对小儿房室瓣(二尖瓣、三尖瓣和共同房室瓣)进行建模。然后,瓣膜模型既用软材料进行3D打印,也使用3D打印的“负”模具在硅胶中成型。使用预定义的评估标准,由先天性心脏外科医生对瓣膜模型进行评估,以确定其是否适合模拟。外科医生的评估表明,与直接打印的瓣膜相比,成型瓣膜在模拟方面具有更优越的材料特性(p < 0.01)。源自三维超声的特定患者成型瓣膜是迈向复杂瓣膜修复逼真模拟的一步,但与直接打印的模型相比,创建所需的时间和人力更多。使用此类模型对儿童瓣膜修复进行特定患者模拟可能有助于手术训练和复杂先天性病例的模拟。