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3D打印二尖瓣模型:用于机器人二尖瓣修复的经济实惠的模拟方法

3D printed mitral valve models: affordable simulation for robotic mitral valve repair.

作者信息

Premyodhin Ned, Mandair Divneet, Ferng Alice S, Leach Timothy S, Palsma Ryan P, Albanna Mohammad Z, Khalpey Zain I

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, University of Arizona College of Medicine-Tucson, Tucson, AZ, USA.

Department of Surgery, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.

出版信息

Interact Cardiovasc Thorac Surg. 2018 Jan 1;26(1):71-76. doi: 10.1093/icvts/ivx243.

Abstract

OBJECTIVES

3D printed mitral valve (MV) models that capture the suture response of real tissue may be utilized as surgical training tools. Leveraging clinical imaging modalities, 3D computerized modelling and 3D printing technology to produce affordable models complements currently available virtual simulators and paves the way for patient- and pathology-specific preoperative rehearsal.

METHODS

We used polyvinyl alcohol, a dissolvable thermoplastic, to 3D print moulds that were casted with liquid platinum-cure silicone yielding flexible, low-cost MV models capable of simulating valvular tissue. Silicone-moulded MV models were fabricated for 2 morphologies: the normal MV and the P2 flail. The moulded valves were plication and suture tested in a laparoscopic trainer box with a da Vinci Si robotic surgical system. One cardiothoracic surgery fellow and 1 attending surgeon qualitatively evaluated the ability of the valves to recapitulate tissue feel through surveys utilizing the 5-point Likert-type scale to grade impressions of the valves.

RESULTS

Valves produced with the moulding and casting method maintained anatomical dimensions within 3% of directly 3D printed acrylonitrile butadiene styrene controls for both morphologies. Likert-type scale mean scores corresponded with a realistic material response to sutures (5.0/5), tensile strength that is similar to real MV tissue (5.0/5) and anatomical appearance resembling real MVs (5.0/5), indicating that evaluators 'agreed' that these aspects of the model were appropriate for training. Evaluators 'somewhat agreed' that the overall model durability was appropriate for training (4.0/5) due to the mounting design. Qualitative differences in repair quality were notable between fellow and attending surgeon.

CONCLUSIONS

3D computer-aided design, 3D printing and fabrication techniques can be applied to fabricate affordable, high-quality educational models for technical training that are capable of differentiating proficiency levels among users.

摘要

目的

能够捕捉真实组织缝合反应的3D打印二尖瓣(MV)模型可用作手术训练工具。利用临床成像方式、3D计算机建模和3D打印技术来制作价格合理的模型,可补充现有的虚拟模拟器,并为针对患者和病理的术前预演铺平道路。

方法

我们使用可溶解的热塑性塑料聚乙烯醇3D打印模具,再用液态铂固化硅胶浇铸,从而得到能够模拟瓣膜组织的灵活、低成本MV模型。为两种形态的MV制作了硅胶模制模型:正常MV和P2连枷样病变。在带有da Vinci Si机器人手术系统的腹腔镜训练箱中对模制瓣膜进行折叠和缝合测试。一名心胸外科住院医师和一名主治外科医生通过使用5点李克特量表进行调查,定性评估瓣膜再现组织触感的能力,以对瓣膜的印象进行评分。

结果

通过模制和浇铸方法制作的瓣膜,两种形态的解剖尺寸与直接3D打印的丙烯腈丁二烯苯乙烯对照物相比,偏差均在3%以内。李克特量表平均得分对应于对缝合线的逼真材料反应(5.0/5)、与真实MV组织相似的拉伸强度(5.0/5)以及与真实MV相似的解剖外观(5.0/5),这表明评估者“同意”该模型的这些方面适合训练。由于安装设计,评估者“ somewhat agreed”(有点同意)整体模型耐用性适合训练(4.0/5)。住院医师和主治外科医生在修复质量上存在明显的定性差异。

结论

3D计算机辅助设计、3D打印和制造技术可用于制造价格合理、高质量的教育模型,用于技术训练,且能够区分不同用户的熟练程度。

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