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腹盆腔手术中的周围神经损伤:国家外科质量改进计划数据库分析

Peripheral Nerve Injury during Abdominal-Pelvic Surgery: Analysis of the National Surgical Quality Improvement Program Database.

作者信息

Wallis Christopher J D, Peltz Sarah, Byrne James, Kroft Jamie, Karanicolas Paul, Coburn Natalie, Nathens Avery B, Nam Robert K, Hallet Julie, Satkunasivam Raj

出版信息

Am Surg. 2017 Nov 1;83(11):1214-1219.

Abstract

Peripheral nerve injury (PNI) is a rare but preventable complication of surgery. We sought to assess whether the use of minimally invasive surgery (MIS) affects the occurrence of PNI. Using the American College of Surgeons National Surgical Quality Improvement Program database, we examined rates of PNI among patients undergoing appendectomy, hysterectomy, colectomy, or radical prostatectomy between 2005 and 2012. We assessed the effect of MIS, as compared with open surgery, on PNI occurrence using logistic regression. Among 297,532 patients, of whom 175,884 (59.1%) underwent MIS, the rate of PNI was 0.03 per cent. Forty-four patients treated using MIS had PNI (0.03%) as compared with 63 who underwent open surgery (0.05%; P = 0.0002). There was a significant decrease in the proportion of surgeries resulting in PNI (P < 0.0001) over time. In univariate analysis, MIS was associated with a decreased occurrence of PNI (odds ratio 0.48, 95% confidence interval 0.33-0.71), but this became nonsignificant on multivariable analysis (odds ratio 0.71, 95% confidence interval 0.47-1.09). Increased operative time and smoking status were the only factors independently associated with an increased risk of PNI on multivariable analysis. MIS techniques during common abdominal-pelvic surgeries do not appear to increase the risk of PNI. Prolonged operative time and smoking are independently associated with an increased risk of PNI. Quality improvement initiatives to increase awareness of PNI and identify patients at increased risk of this preventable complication should be considered.

摘要

周围神经损伤(PNI)是一种罕见但可预防的手术并发症。我们试图评估微创手术(MIS)的使用是否会影响PNI的发生。利用美国外科医师学会国家外科质量改进计划数据库,我们调查了2005年至2012年间接受阑尾切除术、子宫切除术、结肠切除术或根治性前列腺切除术患者的PNI发生率。我们使用逻辑回归评估了与开放手术相比,MIS对PNI发生的影响。在297532例患者中,175884例(59.1%)接受了MIS,PNI发生率为0.03%。接受MIS治疗的44例患者发生了PNI(0.03%),而接受开放手术的63例患者发生PNI(0.05%;P = 0.0002)。随着时间的推移,导致PNI的手术比例显著下降(P < 0.0001)。在单变量分析中,MIS与PNI发生率降低相关(优势比0.48,95%置信区间0.33 - 0.71),但在多变量分析中这一相关性变得不显著(优势比0.71,95%置信区间0.47 - 1.09)。在多变量分析中,手术时间延长和吸烟状况是与PNI风险增加独立相关的唯一因素。常见腹部盆腔手术中的MIS技术似乎不会增加PNI风险。手术时间延长和吸烟与PNI风险增加独立相关。应考虑开展质量改进措施,以提高对PNI的认识,并识别出发生这种可预防并发症风险增加的患者。

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