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降钙素原与新生儿败血症:这是我们正在寻找的生物标志物吗?

Procalcitonin and Neonatal Sepsis: Is This the Biomarker We Are Looking For?

作者信息

Bell Susan Givens

出版信息

Neonatal Netw. 2017 Nov 1;36(6):380-384. doi: 10.1891/0730-0832.36.6.380.

DOI:10.1891/0730-0832.36.6.380
PMID:29185950
Abstract

Researchers estimate the incidence of early onset sepsis as 0.77-1/1,000 live births. It remains as one of the leading causes of neonatal deaths. Clinicians and researchers continue to search for biomarkers for specific neonatal disease processes. Clinicians frequently trend C-reactive protein levels during evaluation for neonatal sepsis. Recently, researchers have begun to explore procalcitonin as a potentially useful diagnostic marker for neonatal sepsis.

摘要

研究人员估计早发型败血症的发病率为每1000例活产中有0.77 - 1例。它仍然是新生儿死亡的主要原因之一。临床医生和研究人员一直在寻找针对特定新生儿疾病过程的生物标志物。临床医生在评估新生儿败血症时经常监测C反应蛋白水平。最近,研究人员已开始探索降钙素原作为新生儿败血症潜在有用的诊断标志物。

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