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经横断主动脉行肾动脉内膜切除术:一种治疗主动脉肾动脉联合动脉粥样硬化的新技术——初步报告

Renal endarterectomy through the transected aorta: a new technique for combined aortorenal atherosclerosis--a preliminary report.

作者信息

Stoney R J, Messina L M, Goldstone J, Reilly L M

机构信息

Department of Surgery, University of California, San Francisco.

出版信息

J Vasc Surg. 1989 Feb;9(2):224-33. doi: 10.1067/mva.1989.vs0090224.

Abstract

The optimal surgical management of combined aortic and renal atherosclerosis has not been defined. A modified technique of renal endarterectomy performed through the transected aorta before anastomosis of the aortic prosthesis is presented. The surgical course and early follow-up results of the first 44 consecutive patients treated by this technique are reported. Twenty-three patients (25%) had symptomatic coronary artery disease, 36 patients (82%) had arterial hypertension, and 28 patients (64%) had elevated serum creatinine levels (mean 2.10 mg/dl). Primary indications for operation related to aortic disease in 39 patients (89%) and to poorly controlled hypertension in five patients (11%). Seventy-five renal arteries were revascularized; 11% of these arteries were occluded. Revascularizations were bilateral in 27 patients (61%), involved a solitary kidney in three patients (6%), and were unilateral in 14 patients (32%). Aortobifemoral bypass grafting was performed in 16 patients (36%), aortoiliac bypass was performed in 15 patients (34%), and infrarenal aortic replacement was performed in 11 patients (25%). Postoperative complications developed in 14 patients (32%). There were two postoperative deaths (4%). Nineteen patients had transient increases in serum creatinine levels greater than 0.5 mg/dl. Two patients required postoperative dialysis, neither related to failure of their renal revascularization. There were five late deaths, all as a result of myocardial infarction. Renal function improved in four patients and remained stable in 22 patients. Blood pressure was improved in 64% of patients previously hypertensive. These preliminary results indicate that renal endarterectomy through the transected aorta along with aortic reconstruction is a safe, efficient, and effective means of treating these complex lesions.

摘要

主动脉和肾动脉联合动脉粥样硬化的最佳手术治疗方法尚未明确。本文介绍了一种在主动脉假体吻合前通过横断主动脉进行肾动脉内膜切除术的改良技术。报告了连续44例采用该技术治疗患者的手术过程及早期随访结果。23例患者(25%)有症状性冠状动脉疾病,36例患者(82%)有动脉高血压,28例患者(64%)血清肌酐水平升高(平均2.10mg/dl)。手术的主要指征与39例患者(89%)的主动脉疾病及5例患者(11%)的高血压控制不佳有关。75条肾动脉实现了血运重建;其中11%的动脉闭塞。27例患者(61%)的血运重建为双侧,3例患者(6%)涉及单肾,14例患者(32%)为单侧。16例患者(36%)进行了主动脉双股动脉搭桥术,15例患者(34%)进行了主动脉髂动脉搭桥术,11例患者(25%)进行了肾下主动脉置换术。14例患者(32%)出现术后并发症。有2例术后死亡(4%)。19例患者血清肌酐水平短暂升高超过0.5mg/dl。2例患者术后需要透析,均与肾血运重建失败无关。有5例晚期死亡,均因心肌梗死。4例患者肾功能改善,22例患者肾功能保持稳定。64%既往有高血压的患者血压得到改善。这些初步结果表明,通过横断主动脉进行肾动脉内膜切除术并联合主动脉重建是治疗这些复杂病变的一种安全、高效且有效的方法。

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