Chu Stacy, Sansing Lauren
Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
F1000Res. 2017 Nov 21;6:2035. doi: 10.12688/f1000research.11687.1. eCollection 2017.
Intracerebral hemorrhage (ICH) remains a prevalent and severe cause of death and disability worldwide. Control of the hypertensive response in acute ICH has been a mainstay of ICH management, yet the optimal approaches and the yield of recommended strategies have been difficult to establish despite a large body of literature. Over the years, theoretical and observed risks and benefits of intensive blood pressure reduction in ICH have been studied in the form of animal models, radiographic studies, and two recent large, randomized patient trials. In this article, we review the historical and developing data and discuss remaining questions surrounding blood pressure management in acute ICH.
脑出血（ICH）仍是全球范围内导致死亡和残疾的常见且严重原因。控制急性脑出血时的高血压反应一直是脑出血治疗的主要手段，然而，尽管有大量文献，但仍难以确定最佳方法以及推荐策略的成效。多年来，已通过动物模型、影像学研究以及最近两项大型随机患者试验，对脑出血强化降压的理论及观察到的风险与益处进行了研究。在本文中，我们回顾了历史和发展数据，并讨论了围绕急性脑出血血压管理的尚存问题。
