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蛛网膜囊肿与精神病

Arachnoid Cyst and Psychosis.

作者信息

Khan Afaque H, Ahmed Syed E

机构信息

Psychiatry, Heartland Behavioral Healthcare, Department of Mental Health and Addiction, State of Ohio, Northeast Ohio Medical University.

Heartland Behavioral Healthcare, Department of Mental Health and Addiction, State of Ohio, Northeast Ohio Medical University.

出版信息

Cureus. 2017 Sep 21;9(9):e1707. doi: 10.7759/cureus.1707.

DOI:10.7759/cureus.1707
PMID:29188151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5703589/
Abstract

Few case reports discuss suspected psychiatric disturbances secondary to arachnoid cysts. To the best of our knowledge, psychosis from arachnoid cysts has not been reported in the recent literature. This case report discusses our experience with a 55-year-old male patient who manifested multiple psychotic episodes suspected in association with an arachnoid cyst. During the initial examinations, a computed tomography (CT) scan of his head revealed a relatively large left anterior superior arachnoid cyst with a mass effect on the frontal lobe. Despite multiple trials of combinations of mood stabilizers and psychotropic medications, the patient continued to deteriorate. We ordered a repeat CT of his head along with a magnetic resonance image and consulted a neurosurgeon for a possible surgical intervention. The neurosurgeon concluded that the patient's psychiatric symptoms were unrelated to the arachnoid cyst. While we were unable to determine the etiology of our patient's psychosis, we believe that the arachnoid cyst played at least some part, as evidenced by reports in the literature. Future advancements in radiological technology may allow for a better exploration of the causal relationship between psychiatric illnesses and brain lesions.

摘要

很少有病例报告讨论蛛网膜囊肿继发的疑似精神障碍。据我们所知,近期文献中尚未报道过因蛛网膜囊肿导致的精神病。本病例报告讲述了我们对一名55岁男性患者的治疗经历,该患者出现了多次疑似与蛛网膜囊肿相关的精神病发作。在初次检查时,他的头部计算机断层扫描(CT)显示左前上蛛网膜囊肿相对较大,对额叶有占位效应。尽管多次尝试联合使用情绪稳定剂和精神药物,但患者病情仍持续恶化。我们再次为他安排了头部CT以及磁共振成像检查,并咨询神经外科医生考虑进行手术干预。神经外科医生得出结论,患者的精神症状与蛛网膜囊肿无关。虽然我们无法确定患者精神病的病因,但我们认为蛛网膜囊肿至少起到了一定作用,文献报道也证明了这一点。放射技术未来的进步可能会有助于更好地探究精神疾病与脑损伤之间的因果关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/c40c030d6885/cureus-0009-00000001707-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/2c769c9a7a7a/cureus-0009-00000001707-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/b9b6e902ed17/cureus-0009-00000001707-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/159cc6d19db3/cureus-0009-00000001707-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/93e02a97d126/cureus-0009-00000001707-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/c40c030d6885/cureus-0009-00000001707-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/2c769c9a7a7a/cureus-0009-00000001707-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/b9b6e902ed17/cureus-0009-00000001707-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/159cc6d19db3/cureus-0009-00000001707-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/93e02a97d126/cureus-0009-00000001707-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b5/5703589/c40c030d6885/cureus-0009-00000001707-i05.jpg

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The Efficacy and Tolerability of Electroconvulsive Therapy in Psychiatric Patients with Arachnoid Cysts: A Retrospective Chart Study.

本文引用的文献

1
Arachnoid Cyst and Psychosis: The Troublemaker or Innocent Bystander.蛛网膜囊肿与精神病:麻烦制造者还是无辜旁观者。
Indian J Psychol Med. 2017 Mar-Apr;39(2):194-195. doi: 10.4103/0253-7176.203107.
2
A schizophrenia-like psychotic disorder secondary to an arachnoid cyst remitted with neurosurgical treatment of the cyst.继发于蛛网膜囊肿的精神分裂症样精神障碍经囊肿的神经外科治疗后缓解。
Open Neuroimag J. 2014 Feb 21;8:1-4. doi: 10.2174/1874440001408010001. eCollection 2014.
3
Arachnoid cyst in a patient with psychosis: Case report.一名患有精神病患者的蛛网膜囊肿:病例报告。
电休克治疗对患有蛛网膜囊肿的精神科患者的疗效及耐受性:一项回顾性病历研究
Brain Sci. 2022 Oct 15;12(10):1393. doi: 10.3390/brainsci12101393.
4
Familial and syndromic forms of arachnoid cyst implicate genetic factors in disease pathogenesis.蛛网膜囊肿的家族性和综合征形式表明遗传因素在疾病发病机制中起作用。
Cereb Cortex. 2023 Mar 10;33(6):3012-3025. doi: 10.1093/cercor/bhac257.
5
Seizures and Postictal Psychosis in a Patient With Retrocerebellar Arachnoid Cyst: A Case Report.小脑后蛛网膜囊肿患者的癫痫发作和发作后精神病:一例报告
Cureus. 2022 May 12;14(5):e24935. doi: 10.7759/cureus.24935. eCollection 2022 May.
Ann Gen Psychiatry. 2007 Jun 28;6:16. doi: 10.1186/1744-859X-6-16.
4
Rapid-cycling bipolar disorder: effects of long-term treatments.快速循环型双相情感障碍:长期治疗的效果
Acta Psychiatr Scand. 2003 Jul;108(1):4-14. doi: 10.1034/j.1600-0447.2003.00126.x.
5
A case of brief psychosis associated with an arachnoid cyst.一例与蛛网膜囊肿相关的短暂性精神病病例。
Psychiatry Clin Neurosci. 2002 Apr;56(2):203-5. doi: 10.1046/j.1440-1819.2002.00945.x.