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在长期病症管理中,初级保健与专科保健之间的衔接处进行共享护理。

Shared care across the interface between primary and specialty care in management of long term conditions.

作者信息

Smith Susan M, Cousins Gráinne, Clyne Barbara, Allwright Shane, O'Dowd Tom

机构信息

HRB Centre for Primary Care Research, Department of General Practice, RCSI Medical School, 123 St Stephens Green, Dublin, Ireland.

School of Pharmacy, Royal College of Surgeons in Ireland, 123 St. Stephen’s Green, Dublin, Ireland, Dublin 2.

出版信息

Cochrane Database Syst Rev. 2017 Feb 23;2(2):CD004910. doi: 10.1002/14651858.CD004910.pub3.

Abstract

BACKGROUND

Shared care has been used in the management of many chronic conditions with the assumption that it delivers better care than primary or specialty care alone; however, little is known about the effectiveness of shared care.

OBJECTIVES

To determine the effectiveness of shared care health service interventions designed to improve the management of chronic disease across the primary/specialty care interface. This is an update of a previously published review.Secondary questions include the following:1. Which shared care interventions or portions of shared care interventions are most effective?2. What do the most effective systems have in common?

SEARCH METHODS

We searched MEDLINE, Embase and the Cochrane Library to 12 October 2015.

SELECTION CRITERIA

One review author performed the initial abstract screen; then two review authors independently screened and selected studies for inclusion. We considered randomised controlled trials (RCTs), non-randomised controlled trials (NRCTs), controlled before-after studies (CBAs) and interrupted time series analyses (ITS) evaluating the effectiveness of shared care interventions for people with chronic conditions in primary care and community settings. The intervention was compared with usual care in that setting.

DATA COLLECTION AND ANALYSIS

Two review authors independently extracted data from the included studies, evaluated study quality and judged the certainty of the evidence using the GRADE approach. We conducted a meta-analysis of results when possible and carried out a narrative synthesis of the remainder of the results. We presented the results in a 'Summary of findings' table, using a tabular format to show effect sizes for all outcome types.

MAIN RESULTS

We identified 42 studies of shared care interventions for chronic disease management (N = 18,859), 39 of which were RCTs, two CBAs and one an NRCT. Of these 42 studies, 41 examined complex multi-faceted interventions and lasted from six to 24 months. Overall, our confidence in results regarding the effectiveness of interventions ranged from moderate to high certainty. Results showed probably few or no differences in clinical outcomes overall with a tendency towards improved blood pressure management in the small number of studies on shared care for hypertension, chronic kidney disease and stroke (mean difference (MD) 3.47, 95% confidence interval (CI) 1.68 to 5.25)(based on moderate-certainty evidence). Mental health outcomes improved, particularly in response to depression treatment (risk ratio (RR) 1.40, 95% confidence interval (CI) 1.22 to 1.62; six studies, N = 1708) and recovery from depression (RR 2.59, 95% CI 1.57 to 4.26; 10 studies, N = 4482) in studies examining the 'stepped care' design of shared care interventions (based on high-certainty evidence). Investigators noted modest effects on mean depression scores (standardised mean difference (SMD) -0.29, 95% CI -0.37 to -0.20; six studies, N = 3250). Differences in patient-reported outcome measures (PROMs), processes of care and participation and default rates in shared care services were probably limited (based on moderate-certainty evidence). Studies probably showed little or no difference in hospital admissions, service utilisation and patient health behaviours (with evidence of moderate certainty).

AUTHORS' CONCLUSIONS: This review suggests that shared care improves depression outcomes and probably has mixed or limited effects on other outcomes. Methodological shortcomings, particularly inadequate length of follow-up, may account in part for these limited effects. Review findings support the growing evidence base for shared care in the management of depression, particularly stepped care models of shared care. Shared care interventions for other conditions should be developed within research settings, with account taken of the complexity of such interventions and awareness of the need to carry out longer studies to test effectiveness and sustainability over time.

摘要

背景

共享照护已被用于多种慢性病的管理,其假设是它能提供比单纯初级照护或专科照护更好的护理;然而,对于共享照护的有效性知之甚少。

目的

确定旨在改善初级/专科照护界面慢性病管理的共享照护健康服务干预措施的有效性。这是对先前发表综述的更新。次要问题包括:1. 哪些共享照护干预措施或共享照护干预措施的哪些部分最有效?2. 最有效的系统有哪些共同之处?

检索方法

我们检索了截至2015年10月12日的MEDLINE、Embase和Cochrane图书馆。

入选标准

由一位综述作者进行初步摘要筛选;然后两位综述作者独立筛选并选择纳入研究。我们纳入了评估共享照护干预措施对初级保健和社区环境中慢性病患者有效性的随机对照试验(RCT)、非随机对照试验(NRCT)、前后对照研究(CBA)和中断时间序列分析(ITS)。将干预措施与该环境中的常规护理进行比较。

数据收集与分析

两位综述作者独立从纳入研究中提取数据,评估研究质量,并使用GRADE方法判断证据的确定性。我们尽可能对结果进行荟萃分析,并对其余结果进行叙述性综合。我们在“结果总结”表中呈现结果,使用表格形式展示所有结局类型的效应量。

主要结果

我们确定了42项关于慢性病管理共享照护干预措施的研究(N = 18,859),其中39项为RCT,2项为CBA,1项为NRCT。在这42项研究中,41项研究考察了复杂的多方面干预措施,持续时间为六个月至24个月。总体而言,我们对干预措施有效性结果的信心从中度到高度确定。结果显示,总体临床结局可能几乎没有差异或没有差异,在少数关于高血压、慢性肾病和中风共享照护的研究中,血压管理有改善趋势(平均差(MD)3.47,95%置信区间(CI)1.68至5.25)(基于中度确定性证据)。心理健康结局有所改善,特别是在针对抑郁症治疗的反应方面(风险比(RR)1.40,95%置信区间(CI)1.22至1.62;六项研究,N = 1708)以及在考察共享照护干预措施“逐步照护”设计的研究中抑郁症的康复情况(RR 2.59,95% CI 1.57至4.26;十项研究,N = 4482)(基于高度确定性证据)。研究人员指出对平均抑郁评分有适度影响(标准化平均差(SMD)-

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