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[2型糖尿病患者中果糖胺、糖化血红蛋白与血糖的比较]

[Comparison of fructosamine, glycosylated hemoglobin and glucose in patients with type II diabetes].

作者信息

Tvorogova M G, Zaĭtseva T M, Aronskaia E E, Kozlov S G, Sharipova G Kh, Titov V N

出版信息

Klin Lab Diagn. 1995 Jan-Feb(1):10-2.

PMID:7757352
Abstract

The levels of blood glucose, glycosylated hemoglobin, and fructosamine were measured in 57 patients with type II diabetes in order to elucidate the value of measurements of glycosylated proteins in assessment of the disorders of carbohydrate metabolism. A highly significant correlation between the levels of glucose and fructosamine was revealed (r = 0.81, p < 0.05) and a reliable, though less significant one, between the levels of glucose and glycosylated hemoglobin (r = 0.55, p < 0.05) and those of fructosamine and glycosylated hemoglobin (r = 0.63, p < 0.05). Similarity between correlation coefficients for fructosamine and glucosylated hemoglobin with the mean concentration of glucose during both the first and second preceding months permits an assumption that the degree of metabolic control of carbohydrate metabolism in the examined patients was stable for at least 2 months.

摘要

为了阐明糖基化蛋白测量在评估碳水化合物代谢紊乱中的价值,对57例II型糖尿病患者测量了血糖、糖化血红蛋白和果糖胺水平。结果显示,血糖水平与果糖胺水平之间存在高度显著相关性(r = 0.81,p < 0.05),血糖水平与糖化血红蛋白水平之间存在可靠但显著性稍低的相关性(r = 0.55,p < 0.05),果糖胺与糖化血红蛋白水平之间也存在相关性(r = 0.63,p < 0.05)。果糖胺和糖化血红蛋白的相关系数与前两个月的平均血糖浓度相似,这使得我们可以假设,至少在2个月内,所检查患者的碳水化合物代谢的代谢控制程度是稳定的。

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