• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

血友病性关节炎全膝关节置换术的中期结果和并发症:2006 年至 2015 年间单中心连续 131 例膝关节回顾性研究。

Mid-term outcomes and complications of total knee arthroplasty in haemophilic arthropathy: A review of consecutive 131 knees between 2006 and 2015 in a single institute.

机构信息

Department of Orthopaedic Surgery, College of Medicine, Kyung Hee University, Seoul, Korea.

出版信息

Haemophilia. 2018 Mar;24(2):299-306. doi: 10.1111/hae.13383. Epub 2017 Nov 29.

DOI:10.1111/hae.13383
PMID:29193440
Abstract

INTRODUCTION

Although total knee arthroplasty (TKA) in haemophilic arthropathy can reduce severe joint pain and improve functional disability, it is technically demanding.

AIM

To evaluate mid-term outcomes and complications of TKA in haemophilic arthropathy.

METHODS

This study retrospectively reviewed 131 consecutive primary TKAs in a single institute. The mean age was 41.0 years old, and the mean follow-up period was 6.8 years. Clinical and radiographic results were evaluated. Complications were categorized according to the classification system of the Knee Society for TKA complications.

RESULTS

The average Western Ontario and McMaster Universities Arthritis Index (WOMAC) score improved from 66.0 to 24.2. The average flexion contracture significantly decreased from 17.3° to 4.7°, but the average pre- and postoperative maximum flexion did not differ (80.9° vs 85.6°, respectively). The average mechanical axis was varus 5.2° preoperatively and valgus 0.3° postoperatively. The coronal positions of the femoral and tibial components and the sagittal positions of these components were within ±3° in 83.2%, 89.3%, 63.4% and 73.3% of cases, respectively. Complications occurred in 17 knees (13.0%): hemarthrosis (n = 7), medial collateral ligament injury (n = 1), stiffness (n = 2), deep periprosthetic joint infection (PJI) (n = 3) and periprosthetic fracture (n = 4).

CONCLUSIONS

The mid-term results of TKA in haemophilic arthropathy were satisfactory in pain relief, improved function and decreased flexion contracture. Bleeding and PJI continue to be major concerns for TKA in haemophilic arthropathy, and risk of periprosthetic fracture must be taken into account for patient education and appropriate prevention.

摘要

简介

尽管全膝关节置换术(TKA)可减轻血友病性关节炎患者的严重关节疼痛并改善功能障碍,但它具有一定的技术难度。

目的

评估 TKA 在血友病性关节炎中的中期疗效和并发症。

方法

本研究回顾性分析了单中心 131 例初次 TKA 的临床资料。患者的平均年龄为 41.0 岁,平均随访时间为 6.8 年。评估临床和影像学结果。并发症根据膝关节学会 TKA 并发症分类系统进行分类。

结果

WOMAC 评分(Western Ontario and McMaster Universities Arthritis Index)从 66.0 分改善至 24.2 分。平均膝关节屈曲挛缩度从 17.3°显著改善至 4.7°,但术前和术后最大屈曲度无差异(分别为 80.9°和 85.6°)。术前平均机械轴为内翻 5.2°,术后为外翻 0.3°。83.2%、89.3%、63.4%和 73.3%的病例中,股骨和胫骨组件的冠状位及矢状位位置分别在±3°范围内。17 例(13.0%)发生并发症:关节内血肿(n=7)、内侧副韧带损伤(n=1)、僵硬(n=2)、深部假体周围关节感染(PJI,n=3)和假体周围骨折(n=4)。

结论

TKA 治疗血友病性关节炎的中期疗效良好,可缓解疼痛、改善功能并减轻膝关节屈曲挛缩。出血和 PJI 仍然是 TKA 的主要关注点,必须考虑假体周围骨折的风险,对患者进行教育并采取适当的预防措施。

相似文献

1
Mid-term outcomes and complications of total knee arthroplasty in haemophilic arthropathy: A review of consecutive 131 knees between 2006 and 2015 in a single institute.血友病性关节炎全膝关节置换术的中期结果和并发症:2006 年至 2015 年间单中心连续 131 例膝关节回顾性研究。
Haemophilia. 2018 Mar;24(2):299-306. doi: 10.1111/hae.13383. Epub 2017 Nov 29.
2
Total knee arthroplasty for severe haemophilic arthropathy: long-term experience in Taiwan.严重血友病性关节病的全膝关节置换术:台湾地区的长期经验
Haemophilia. 2008 Jul;14(4):828-34. doi: 10.1111/j.1365-2516.2008.01693.x. Epub 2008 May 22.
3
[Impact of Preoperative Knee Stiffness on the Postoperative Outcome after Total Knee Arthroplasty in Patients with Haemophilia].[血友病患者全膝关节置换术前膝关节僵硬对术后结果的影响]
Z Orthop Unfall. 2015 Oct;153(5):526-32. doi: 10.1055/s-0035-1557768. Epub 2015 Oct 9.
4
Long-term results of total knee arthroplasty in haemophilic patients: an 18-year follow-up.血友病患者全膝关节置换术的长期结果:18年随访
Knee Surg Sports Traumatol Arthrosc. 2017 Nov;25(11):3431-3438. doi: 10.1007/s00167-016-4340-6. Epub 2016 Nov 3.
5
Outcome after total knee arthroplasty in haemophilic patients with stiff knees.血友病性膝关节僵硬患者全膝关节置换术后的结果
Haemophilia. 2015 Jul;21(4):e300-5. doi: 10.1111/hae.12698. Epub 2015 Apr 30.
6
Knee haemophilic arthropathy care in Chile: Midterm outcomes and complications after total knee arthroplasty.智利血友病性膝关节病的护理:全膝关节置换术后的中期结果及并发症
Haemophilia. 2020 Jul;26(4):e179-e186. doi: 10.1111/hae.14004. Epub 2020 Apr 20.
7
Clinical and radiologic results after open-wedge high tibial osteotomy in haemophilic knee arthropathy with varus deformity.血友病性膝关节病伴内翻畸形行开放式楔形胫骨高位截骨术后的临床和影像学结果。
Haemophilia. 2018 Sep;24(5):792-799. doi: 10.1111/hae.13566. Epub 2018 Jul 13.
8
Robot-assisted total knee arthroplasty in haemophilic arthropathy.血友病性关节病的机器人辅助全膝关节置换术。
Haemophilia. 2016 May;22(3):446-52. doi: 10.1111/hae.12875. Epub 2016 Feb 8.
9
Computer-navigated total knee arthroplasty in haemophilic arthropathy.计算机导航全膝关节置换术治疗血友病性关节炎。
Haemophilia. 2013 Mar;19(2):259-66. doi: 10.1111/hae.12063. Epub 2012 Nov 22.
10
Postoperative bleeding adversely affects total knee arthroplasty outcomes in hemophilia.术后出血对血友病患者全膝关节置换术的预后产生不利影响。
Knee. 2022 Dec;39:261-268. doi: 10.1016/j.knee.2022.10.001. Epub 2022 Oct 22.

引用本文的文献

1
Total knee arthroplasty for ankylosed knees in the extended position with hemophilia: a medium- and long-term single-center experience.血友病患者伸直位强直膝关节的全膝关节置换术:单中心中长期经验
BMC Surg. 2025 Sep 2;25(1):405. doi: 10.1186/s12893-025-03102-5.
2
Primary Total Knee Arthroplasty in Hemophilia and Allied Disorders: Revision Rates and Their Causes.血友病及相关疾病患者的初次全膝关节置换术:翻修率及其原因
Arch Bone Jt Surg. 2024;12(6):428-432. doi: 10.22038/ABJS.2024.76697.3544.
3
Total elbow arthroplasty for hemophilic osteoproliferative elbow arthritis with severe flexion contracture: A case report.
全肘关节置换术治疗重度屈曲挛缩型血友病性骨增生性肘关节炎:一例报告
SAGE Open Med Case Rep. 2023 Dec 13;11:2050313X231216597. doi: 10.1177/2050313X231216597. eCollection 2023.
4
Primary total knee arthroplasty in hemophilic arthropathy.血友病性关节病的初次全膝关节置换术。
EFORT Open Rev. 2023 Nov 1;8(11):830-840. doi: 10.1530/EOR-23-0101.
5
Total Hip Arthroplasty in Patients with Hemophilia: What Do We know?血友病患者的全髋关节置换术:我们了解什么?
Arch Bone Jt Surg. 2023;11(7):434-440. doi: 10.22038/ABJS.2023.58812.291.
6
Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral Component.血友病患者的全膝关节置换术:采用氧化锆股骨部件的现代膝关节植入物的长期结果和生存率
J Clin Med. 2023 Jun 28;12(13):4356. doi: 10.3390/jcm12134356.
7
Short-term outcome of total knee replacement in a patient with hemophilia: A case report and review of literature.血友病患者全膝关节置换术的短期疗效:病例报告及文献复习
World J Clin Cases. 2023 Apr 26;11(12):2788-2795. doi: 10.12998/wjcc.v11.i12.2788.
8
Surgery for chronic arthropathy in people with haemophilia.血友病患者慢性关节病的手术治疗。
Cochrane Database Syst Rev. 2022 Nov 30;11(11):CD013634. doi: 10.1002/14651858.CD013634.pub2.
9
Complications and Implant Survival of Total Knee Arthroplasty in People with Hemophilia.血友病患者全膝关节置换术的并发症及植入物存活率
J Clin Med. 2022 Oct 23;11(21):6244. doi: 10.3390/jcm11216244.
10
Short-term Effectiveness of a Modified Osteotomy for Total Elbow Joint Replacement in Patients of Hemophilic Elbow Arthritis with Severe Flexion Contracture Deformity: A Three-Cases Series Report.改良截骨术治疗血友病性肘关节炎伴严重屈曲挛缩畸形的全肘关节置换术近期疗效:三例病例系列报告。
Orthop Surg. 2022 Oct;14(10):2741-2749. doi: 10.1111/os.13457. Epub 2022 Aug 26.