Department of Orthopaedic Surgery, College of Medicine, Kyung Hee University, Seoul, Korea.
Haemophilia. 2018 Mar;24(2):299-306. doi: 10.1111/hae.13383. Epub 2017 Nov 29.
Although total knee arthroplasty (TKA) in haemophilic arthropathy can reduce severe joint pain and improve functional disability, it is technically demanding.
To evaluate mid-term outcomes and complications of TKA in haemophilic arthropathy.
This study retrospectively reviewed 131 consecutive primary TKAs in a single institute. The mean age was 41.0 years old, and the mean follow-up period was 6.8 years. Clinical and radiographic results were evaluated. Complications were categorized according to the classification system of the Knee Society for TKA complications.
The average Western Ontario and McMaster Universities Arthritis Index (WOMAC) score improved from 66.0 to 24.2. The average flexion contracture significantly decreased from 17.3° to 4.7°, but the average pre- and postoperative maximum flexion did not differ (80.9° vs 85.6°, respectively). The average mechanical axis was varus 5.2° preoperatively and valgus 0.3° postoperatively. The coronal positions of the femoral and tibial components and the sagittal positions of these components were within ±3° in 83.2%, 89.3%, 63.4% and 73.3% of cases, respectively. Complications occurred in 17 knees (13.0%): hemarthrosis (n = 7), medial collateral ligament injury (n = 1), stiffness (n = 2), deep periprosthetic joint infection (PJI) (n = 3) and periprosthetic fracture (n = 4).
The mid-term results of TKA in haemophilic arthropathy were satisfactory in pain relief, improved function and decreased flexion contracture. Bleeding and PJI continue to be major concerns for TKA in haemophilic arthropathy, and risk of periprosthetic fracture must be taken into account for patient education and appropriate prevention.
尽管全膝关节置换术(TKA)可减轻血友病性关节炎患者的严重关节疼痛并改善功能障碍,但它具有一定的技术难度。
评估 TKA 在血友病性关节炎中的中期疗效和并发症。
本研究回顾性分析了单中心 131 例初次 TKA 的临床资料。患者的平均年龄为 41.0 岁,平均随访时间为 6.8 年。评估临床和影像学结果。并发症根据膝关节学会 TKA 并发症分类系统进行分类。
WOMAC 评分(Western Ontario and McMaster Universities Arthritis Index)从 66.0 分改善至 24.2 分。平均膝关节屈曲挛缩度从 17.3°显著改善至 4.7°,但术前和术后最大屈曲度无差异(分别为 80.9°和 85.6°)。术前平均机械轴为内翻 5.2°,术后为外翻 0.3°。83.2%、89.3%、63.4%和 73.3%的病例中,股骨和胫骨组件的冠状位及矢状位位置分别在±3°范围内。17 例(13.0%)发生并发症:关节内血肿(n=7)、内侧副韧带损伤(n=1)、僵硬(n=2)、深部假体周围关节感染(PJI,n=3)和假体周围骨折(n=4)。
TKA 治疗血友病性关节炎的中期疗效良好,可缓解疼痛、改善功能并减轻膝关节屈曲挛缩。出血和 PJI 仍然是 TKA 的主要关注点,必须考虑假体周围骨折的风险,对患者进行教育并采取适当的预防措施。