Beckers Gautier, Massé Vincent, Vendittoli Pascal-André, Morcos Mina W
Department of Surgery, Hôpital Maisonneuve-Rosemont, Montréal University, Montréal, Quebec, Canada.
Personalized Arthroplasty Society, Atlanta, Georgia, USA.
EFORT Open Rev. 2023 Nov 1;8(11):830-840. doi: 10.1530/EOR-23-0101.
Advanced hemophilic knee arthropathy is a frequent and devastating manifestation of severe hemophilia with significant implications for activities of daily living. Hemophilic arthropathy is caused by repeated bleeding, resulting in joint degeneration, pain, deformity and disability. In patients with hemophilia and advanced disease, total knee arthroplasty (TKA) has proven to be the most successful intervention, improves physical function and reduces knee pain. Hemophilic patients carry additional risks for complications and required specific pre/postoperative considerations. Expert treatment center should be used to improve patient outcome. Hemophilic patients present significant surgical challenges such as joint destruction, bone loss, severe ankylosis and oligoarticular involvement. The surgeon performing the arthroplasty must be experienced to manage such problems.
重度血友病性膝关节炎是严重血友病常见且具有破坏性的表现，对日常生活活动有重大影响。血友病性关节病由反复出血引起，导致关节退变、疼痛、畸形和残疾。对于患有血友病且病情严重的患者，全膝关节置换术（TKA）已被证明是最成功的干预措施，可改善身体功能并减轻膝关节疼痛。血友病患者出现并发症的风险更高，需要特殊的术前/术后考虑。应利用专家治疗中心来改善患者预后。血友病患者存在重大的手术挑战，如关节破坏、骨质流失、严重关节强直和少关节受累。进行关节置换术的外科医生必须有经验来处理此类问题。
