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血友病性膝关节病伴内翻畸形行开放式楔形胫骨高位截骨术后的临床和影像学结果。

Clinical and radiologic results after open-wedge high tibial osteotomy in haemophilic knee arthropathy with varus deformity.

机构信息

Department of Orthopaedic Surgery, College of Medicine, Kyung Hee University, Seoul, Korea.

Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.

出版信息

Haemophilia. 2018 Sep;24(5):792-799. doi: 10.1111/hae.13566. Epub 2018 Jul 13.

Abstract

INTRODUCTION

The previous studies have described only closed-wedge high tibial osteotomy (HTO) in haemophilic arthropathy (HA).

AIM

The purpose of this study was to evaluate clinical and radiographic results after open-wedge HTO in HA with varus knee deformity.

METHODS

We included 13 open-wedge HTOs in HA performed between 2005 and 2016. The mean age of patients was 28.9 years. Visual analogue scale (VAS), Western Ontario and McMaster Universities (WOMAC), and range of motion (ROM) indices were assessed. Any complications or requirements for total knee arthroplasty (TKA) were investigated. Mechanical axis (MA), minimal joint space width (mJSW) and Pettersson score were measured. Bone union rates at 3 and 6 months postoperative were evaluated.

RESULTS

VAS improved from 5.1 to 2.4 (P < .001). WOMAC was 66.5 preoperatively, and 26.6 postoperatively (P < .001). Pre- and postoperative ROM did not differ significantly. There were no cases of HTO converted to TKA, but one case of HTO required TKA 152 months postoperative. No complications were observed. The MA was corrected from varus 5.1° to valgus 1.2° (P < .001). Pre- and postoperative mJSW did not significantly differ. Pettersson score improved from 3.84 to 2.47 (P < .001). The bone union rates at the osteotomy gap were 45.2% and 67.8% at 3 and 6 months postoperative.

CONCLUSIONS

Open-wedge HTO should be considered in cases of HA with varus deformity in young haemophilic patients, even though inflammatory arthritis is not an optimal indication for this procedure. It can be an appropriate treatment with respect to the choice to postpone TKA.

摘要

引言

之前的研究仅描述了血友病性关节炎(HA)中的闭合楔形胫骨高位截骨术(HTO)。

目的

本研究旨在评估 HA 合并内翻畸形的开放式楔形 HTO 的临床和影像学结果。

方法

我们纳入了 2005 年至 2016 年间进行的 13 例 HA 开放式楔形 HTO。患者的平均年龄为 28.9 岁。评估了视觉模拟量表(VAS)、西安大略和麦克马斯特大学(WOMAC)以及关节活动度(ROM)指数。调查了任何并发症或需要全膝关节置换术(TKA)的情况。测量了机械轴(MA)、最小关节间隙宽度(mJSW)和 Pettersson 评分。评估了术后 3 个月和 6 个月的骨愈合率。

结果

VAS 从 5.1 改善至 2.4(P<0.001)。WOMAC 术前为 66.5,术后为 26.6(P<0.001)。术前和术后的 ROM 没有显著差异。没有 HTO 转为 TKA 的病例,但有 1 例 HTO 在术后 152 个月需要 TKA。未观察到并发症。MA 从内翻 5.1°校正为外翻 1.2°(P<0.001)。术前和术后 mJSW 没有显著差异。Pettersson 评分从 3.84 改善至 2.47(P<0.001)。术后 3 个月和 6 个月时,骨切开间隙的骨愈合率分别为 45.2%和 67.8%。

结论

对于年轻血友病患者的 HA 合并内翻畸形,即使炎症性关节炎不是该手术的理想适应证,也应考虑开放式楔形 HTO。考虑到推迟 TKA 的选择,它可能是一种适当的治疗方法。

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