Kikuchi Wakako, Nakagomi Toyoko, Gauchan Punita, Agbemabiese Chantal Ama, Noguchi Atsuko, Nakagomi Osamu, Takahashi Tsutomu
Department of Paediatrics, Akita University Graduate School of Medicine, Akita, Japan.
Department of Molecular Epidemiology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
Arch Virol. 2018 Mar;163(3):791-794. doi: 10.1007/s00705-017-3668-7. Epub 2017 Dec 1.
Equine-like G3P[8] rotavirus A strains with DS-1-like backbone genes have emerged since 2013. An equine-like RVA/Human-wt/JPN/15R429/2015/G3P[8] strain possessing I2-R2-C2-M2-A2-N2-T2-E2-H2 was detected in Japan in 2015. Its VP7 gene was ≥ 99.3% identical to those of equine-like G3P[4] strains detected in Japan, and the remaining 10 genes were 98.6-99.8% identical to G1P[8] double-gene reassortants detected in Japan, Thailand and the Philippines. Thus, 15R429 was likely generated through reassortment between the equine-like G3P[4] and G1P[8] reassortant strains. Notably, 15R429 was 98.5-99.8% identical across all 11 genes of the equine-like G3P[8] strains detected in Spain and Hungary in 2015.
自2013年以来，出现了具有DS-1样骨干基因的马样G3P[8]轮状病毒A株。2015年在日本检测到一株具有I2-R2-C2-M2-A2-N2-T2-E2-H2的马样RVA/Human-wt/JPN/15R429/2015/G3P[8]株。其VP7基因与在日本检测到的马样G3P[4]株的VP7基因一致性≥99.3%，其余10个基因与在日本、泰国和菲律宾检测到的G1P[8]双基因重配株的一致性为98.6-99.8%。因此，15R429可能是通过马样G3P[4]株和G1P[8]重配株之间的重配产生的。值得注意的是，15R429与2015年在西班牙和匈牙利检测到的马样G3P[8]株的所有11个基因的一致性为98.5-99.8%。
