Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan, ROC.
Department of Neurology, Chang Gung Memorial Hospital-Linkou Medical Center, Taoyuan, Taiwan, ROC.
J Chin Med Assoc. 2018 Jan;81(1):12-17. doi: 10.1016/j.jcma.2017.06.019. Epub 2017 Dec 1.
Neuropathic pain (NeP) is distinct from nociceptive pain and has different underlying mechanisms requiring specific treatment strategies. To aid diagnosis, self-administered screening questionnaires (such as ID Pain) have been developed to help physicians identify patients with NeP. The aim of this study was to develop and validate a translated ID Pain questionnaire for Taiwanese subjects (ID Pain-T).
ID Pain, a 6-item self-administered questionnaire, score ranged from -1 to 5, was translated from English into Mandarin Chinese using local terms and back-translated by an expert panel. A prospective, non-randomized, multi-center study was performed in four medical centers in Taiwan. Patients aged over 18 years with pain other than headache for more than 30 days in either neurology or pain clinic were prospectively recruited. They completed the ID Pain-T questionnaire themselves. The study investigators, blinded to the subjects' ID Pain-T scores, examined subjects using a standardized clinical and neurological diagnostic procedure. The ID Pain-T questionnaire scores were verified and validated.
A total of 317 patients completed the study. Clinical diagnosis of NeP was given for 189 (60%) patients, mixed pain diagnosed in 7 (2%) patients, and nociceptive pain in 121 (38%) patients. The reliability and consistency of the ID Pain-T were acceptable, with a Cronbach's alpha value of 0.6. Statistical analysis of the ID Pain-T questionnaire calculated an optimal cut-off score of ≥2 for determining NeP with 77% sensitivity and 74% specificity for predicting NeP. Ordinary least squares regression analysis showed significant predictive accuracy of the ID Pain-T questionnaire for NeP (P < 0.0001). These results are comparable to other studies that have translated the ID Pain questionnaire into other languages.
This study provides evidence that the ID Pain-T questionnaire is a valid and reliable self-administered screening tool to identify NeP in Taiwanese patients.
神经病理性疼痛（NeP）与伤害性疼痛不同，其发病机制也不同，需要采用特定的治疗策略。为了帮助诊断，已经开发了一些自我管理的筛查问卷（如 ID Pain），以帮助医生识别患有 NeP 的患者。本研究旨在开发和验证一种适用于台湾患者的翻译版 ID Pain 问卷（ID Pain-T）。
ID Pain 是一种 6 项自我管理的问卷，评分范围为-1 至 5 分，采用当地术语从英文翻译成中文，并由专家小组进行回译。在台湾的四家医疗中心进行了一项前瞻性、非随机、多中心研究。在神经科或疼痛诊所就诊、疼痛持续超过 30 天且疼痛非头痛的 18 岁以上患者被前瞻性招募。他们自行完成 ID Pain-T 问卷。研究调查员在不了解患者 ID Pain-T 评分的情况下，使用标准化的临床和神经学诊断程序对患者进行检查。验证和验证了 ID Pain-T 问卷的评分。
共有 317 名患者完成了这项研究。189 名（60%）患者的临床诊断为 NeP，7 名（2%）患者的混合性疼痛诊断为 NeP，121 名（38%）患者的伤害性疼痛诊断为 NeP。ID Pain-T 的可靠性和一致性可接受，Cronbach's alpha 值为 0.6。对 ID Pain-T 问卷的统计分析计算出一个最佳临界值≥2，用于确定 NeP，其对 NeP 的敏感性为 77%，特异性为 74%。最小二乘回归分析显示，ID Pain-T 问卷对 NeP 具有显著的预测准确性（P<0.0001）。这些结果与其他已将 ID Pain 问卷翻译成其他语言的研究相当。
本研究表明，ID Pain-T 问卷是一种有效的、可靠的自我管理筛查工具，可用于识别台湾患者的 NeP。
